Natural Bio-active Compounds: Biotechnology, Bioengineering, and Molecular Approaches

Description

Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds and their products is considered to be suitable and safe in e.g. alternative medicine. Thus, there is an unprecedented need to meet the increasing demand for plant secondary metabolites in the flavor and fragrance, food, and pharmaceutical industries. However, it is difficult to obtain a constant quantity of compounds from the cultivated plants, as their yield fluctuates due to several factors including genotypic variations, the geography, edaphic conditions, harvesting and processing methods. Yet familiarity with these substances and the exploration of various approaches could open new avenues in their production. This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries. Accordingly, it offers a valuable resource for students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products. Front Matter ....Pages i-xvi Bio-active Peptides: Role in Plant Growth and Defense (Sharadwata Pan, Dominic Agyei, Jaison Jeevanandam, Michael K. Danquah)....Pages 1-29 Linking Omics Approaches to Medicinal Plants and Human Health (Ajay Kumar, Sushil Kumar, Thuruthiyil Dennis Thomas, Nirala Ramchiary, Mallappa Kumara Swamy, Ilyas Ahmad)....Pages 31-57 Application of Biotechnology in Producing Plant Bio-active Compounds (Glaucia C. Pereira)....Pages 59-78 Transgenic Plant Cell Cultures: A Promising Approach for Secondary Metabolite Production (Lakkakula Satish, Arockiam Sagina Rency, Balasubramanian C. Muthubharathi, Sasanala Shamili, Ramakrishnan Rameshkumar, Mallappa Kumara Swamy et al.)....Pages 79-122 An Insight into Biotechnological Approaches Used for the Improvement of Secondary Metabolites from the Medicinal Aquatic Plant, Water Hyssop (Bacopa monnieri L.) (Muhammad Aasim, Muhammad Sameeullah, Mehmet Karataş, Seyma Bakirci, Allah Bakhsh, Mohd Sayeed Akhtar)....Pages 123-152 Prospects for the Use of Plant Cell Culture as Alternatives to Produce Secondary Metabolites (Hera Nadeem, Faheem Ahmad)....Pages 153-182 Biotechnological Exercises in the Production of Secondary Metabolites and Its Significance in Healthcare Practices (Mohammed Shariq Iqbal, Mohammad Israil Ansari)....Pages 183-204 Salient Biotechnological Interventions in Saffron (Crocus sativus L.): A Major Source of Bio-active Apocarotenoids (Maryam Vahedi, Roghaye Karimi, Jitendriya Panigrahi, Saikat Gantait)....Pages 205-223 Recent Advances in Extraction, Characterization, and Potential Use of Citral (Mohammad Idrees, Faruck Lukmanul Hakkim, Gowhar Ahmed Naikoo, Israr Ul Hassan)....Pages 225-236 Hairy Root Cultures as an Alternative Source for the Production of High-Value Secondary Metabolites (Arockiam Sagina Rency, Subramani Pandian, Rakkammal Kasinathan, Lakkakula Satish, Mallappa Kumara Swamy, Manikandan Ramesh)....Pages 237-264 Plant Cell Culture as Alternatives to Produce Secondary Metabolites (Shweta Raj, Prakash Saudagar)....Pages 265-286 Metabolic Engineering Strategies for Enhancing the Production of Bio-active Compounds from Medicinal Plants (Munish Sharma, Archana Koul, Deepak Sharma, Sanjana Kaul, Mallappa Kumara Swamy, Manoj K. Dhar)....Pages 287-316 Enhancement of Rosmarinic Acid Content by Biotechnological Approaches and Metabolic Engineering (Faruck Lukmanul Hakkim, Mohammad Idrees, Hamid A. Bakshi, Laiqahmed Mombasawala, Luay Rashan)....Pages 317-330