ENGLISH

Dopamine in the CNS II

By Gaetano Di Chiara (editor)

Book information

Publisher
Springer
Year
2002
ISBN
9783642076596, 9783662067659
DOI
10.1007/978-3-662-06765-9
Language
english
Format
PDF
Filesize
11 MB (11512645 bytes)
Series
Handbook of Experimental Pharmacology 154/2
Edition
1
Pages
514\530
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
general; Cell BiologyNeurosciences; Pharmacology/Toxicology; Neurology;

Description

Dopamine was initially regarded as a mere precursor of noradrenaline, but has progressively gained its present status of a common target for major drug classes and a substrate for some basic functions and dysfunctions of the Central Nervous System. The scientific interest has shifted from typically motor areas of the striatum to traditionally limbic ones as the nucleus accumbens and its afferent areas, the prefrontal cortex, the hippocampal formation and the basolateral amygdala. This double volume provides a systematic account of the anatomy, physiology, neurochemistry, molecular biology and behavioural pharmacology of dopamine in the CNS. The second volume deals with functional and behavioural aspects as the electrophysiology of dopamine neurons and of dopamine actions, the interaction with other transmitters and its role in behaviour and in the action of centrally acting drugs.

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