Harrison’s Manual Of Medicine

Description

All the authority of the most trusted brand in medical content in a convenient, portable guide The Harrison’s Manual, derived from most clinically salient content featured in Harrison's Principles of Internal Medicine, 20th Edition, delivers numerous clinical algorithms in one practical, portable resource. The Manual also includes abundant quick reference tables, plus concise text—providing rapid access to bedside information when decisions need to be made quickly. This full color summary guide covers all diseases and conditions commonly seen in inpatient general medicine, so you can be sure to find invaluable content directly to your workflow and practice. The 20th edition has been updated to reflect the latest clinical developments in medicine. The Manual truly makes it easy to find what you need at the point of care. The easy-to-navigate chapters cover symptoms/signs, medical emergencies, specific diseases, and care of the hospitalized patient, with a particular focus on: • Etiology and Epidemiology • Clinically Relevant Pathophysiology • Signs and Symptoms • Differential Diagnosis • Physical and Laboratory Findings • Therapeutics • Practice Guidelines, and more Cover......Page 1 Title Page......Page 4 Copyright Page......Page 5 Contents......Page 6 Contributors......Page 14 Preface......Page 16 Acknowledgments......Page 18 1 Electrolytes......Page 22 2 Acid-Base Disorders......Page 37 3 Diagnostic Imaging in Internal Medicine......Page 43 4 Procedures Commonly Performed by Internists......Page 47 5 Principles of Critical Care Medicine......Page 53 6 Pain and Its Management......Page 56 7 Assessment of Nutritional Status......Page 61 8 Enteral and Parenteral Nutrition......Page 68 9 Transfusion and Pheresis Therapy......Page 70 10 Palliative and End-of-Life Care......Page 72 11 Cardiovascular Collapse and Sudden Death......Page 80 12 Shock......Page 83 13 Narcotic Overdose......Page 87 14 Sepsis and Septic Shock......Page 89 15 Acute Pulmonary Edema......Page 92 16 Acute Respiratory Distress Syndrome......Page 93 17 Respiratory Failure......Page 96 18 Confusion, Stupor, and Coma......Page 97 19 Stroke......Page 103 20 Subarachnoid Hemorrhage......Page 112 21 Increased Intracranial Pressure and Head Trauma......Page 114 22 Spinal Cord Compression......Page 119 23 Hypoxic-Ischemic Encephalopathy......Page 121 24 Status Epilepticus......Page 122 25 Diabetic Ketoacidosis and Hyperosmolar Coma......Page 124 26 Hypoglycemia......Page 127 27 Oncologic Emergencies......Page 130 28 Anaphylaxis......Page 135 29 Bites, Venoms, Stings, and Marine Poisonings......Page 136 30 Fever, Hyperthermia, and Rash......Page 148 31 Generalized Fatigue......Page 152 32 Unintentional Weight Loss......Page 156 33 Chest Pain......Page 158 35 Dyspnea......Page 162 36 Cyanosis......Page 165 37 Cough and Hemoptysis......Page 167 38 Edema......Page 170 39 Abdominal Pain......Page 174 40 Nausea, Vomiting, and Indigestion......Page 178 41 Dysphagia......Page 182 42 Diarrhea, Malabsorption, and Constipation......Page 187 43 Gastrointestinal Bleeding......Page 195 44 Jaundice and Evaluation of Liver Function......Page 199 45 Ascites......Page 207 46 Lymphadenopathy and Splenomegaly......Page 210 47 Anemia and Polycythemia......Page 215 48 Azotemia and Urinary Abnormalities......Page 218 49 Pain and Swelling of Joints......Page 224 50 Back and Neck Pain......Page 228 51 Headache......Page 236 52 Syncope......Page 244 53 Dizziness and Vertigo......Page 248 54 Acute Visual Loss and Double Vision......Page 251 55 Weakness and Paralysis......Page 255 56 Tremor and Movement Disorders......Page 258 57 Aphasia......Page 261 58 Sleep Disorders......Page 263 59 Sore Throat, Earache, and Upper Respiratory Symptoms......Page 268 60 General Examination of the Skin......Page 276 61 Common Skin Conditions......Page 279 62 Examination of Blood Smears and Bone Marrow......Page 288 63 Red Blood Cell Disorders......Page 290 64 Leukocytosis and Leukopenia......Page 296 65 Bleeding and Thrombotic Disorders......Page 299 66 Myeloid Leukemias, Myelodysplasia, and Myeloproliferative Syndromes......Page 306 67 Lymphoid Malignancies......Page 317 68 Skin Cancer......Page 330 69 Head and Neck Cancer......Page 333 70 Lung Cancer......Page 335 71 Breast Cancer......Page 341 72 Tumors of the Gastrointestinal Tract......Page 346 73 Genitourinary Tract Cancer......Page 358 74 Gynecologic Cancer......Page 364 75 Tumors of the Nervous System......Page 368 76 Prostate Hyperplasia and Carcinoma......Page 373 77 Cancer of Unknown Primary Site......Page 376 78 Paraneoplastic Endocrine Syndromes......Page 380 79 Neurologic Paraneoplastic Syndromes......Page 383 80 Growing Threats in Infectious Disease......Page 388 81 Infections Acquired in Health Care Facilities......Page 392 82 Infections in the Immunocompromised Host......Page 397 83 Infective Endocarditis......Page 408 84 Intraabdominal Infections......Page 419 85 Infectious Diarrheas and Bacterial Food Poisoning......Page 424 86 Sexually Transmitted and Reproductive Tract Infections......Page 438 87 Infections of the Skin, Soft Tissues, Joints, and Bones......Page 454 88 Pneumococcal Infections......Page 461 89 Staphylococcal Infections......Page 465 90 Streptococcal/Enterococcal Infections, Diphtheria, and Infections Caused by Other Corynebacteria and Related Species......Page 474 91 Meningococcal and Listerial Infections......Page 484 92 Infections Caused by Haemophilus, Bordetella, Moraxella, and HACEK Group Organisms......Page 488 93 Diseases Caused by Gram-Negative Enteric Bacteria and Pseudomonads......Page 494 94 Infections Caused by Miscellaneous Gram-Negative Bacilli......Page 504 95 Anaerobic Infections......Page 511 96 Nocardiosis, Actinomycosis, and Whipple’s Disease......Page 519 97 Tuberculosis and Other Mycobacterial Infections......Page 524 98 Lyme Disease and Other Nonsyphilitic Spirochetal Infections......Page 536 99 Rickettsial Diseases......Page 542 100 Mycoplasma pneumoniae, Legionella Species, and Chlamydia pneumoniae......Page 552 101 Chlamydia trachomatis and Chlamydia psittaci......Page 556 102 Infections with Herpes Simplex Virus, Varicella-Zoster Virus, Cytomegalovirus, Epstein-Barr Virus, and Human Herpesvirus Types 6, 7, and 8......Page 558 103 Influenza and Other Viral Respiratory Diseases......Page 572 104 Rubeola, Rubella, Mumps, and Parvovirus Infections......Page 576 105 Enterovirus Infections......Page 582 106 Insect- and Animal-Borne Viral Infections......Page 585 107 HIV Infection and AIDS......Page 593 108 Pneumocystis Pneumonia, Candidiasis, and Other Fungal Infections......Page 609 109 Overview of Parasitic Infections......Page 627 110 Malaria, Toxoplasmosis, Babesiosis, and Other Protozoal Infections......Page 631 111 Helminthic Infections and Ectoparasite Infestations......Page 646 112 Physical Examination of the Heart......Page 660 113 Electrocardiography......Page 665 114 Noninvasive Examination of the Heart......Page 669 115 Congenital Heart Disease in the Adult......Page 674 116 Valvular Heart Disease......Page 679 117 Cardiomyopathies and Myocarditis......Page 687 118 Pericardial Disease......Page 692 119 Hypertension......Page 697 120 Metabolic Syndrome......Page 703 121 ST-Segment Elevation Myocardial Infarction......Page 705 122 Unstable Angina and Non-ST-Elevation Myocardial Infarction......Page 715 123 Chronic Stable Angina......Page 719 124 Bradyarrhythmias......Page 724 125 Tachyarrhythmias......Page 727 126 Heart Failure and Cor Pulmonale......Page 736 127 Diseases of the Aorta......Page 742 128 Peripheral Vascular Disease......Page 745 129 Pulmonary Hypertension......Page 748 130 Diagnostic Procedures in Respiratory Disease......Page 752 131 Asthma......Page 755 132 Environmental Lung Diseases......Page 759 133 Chronic Obstructive Pulmonary Disease......Page 762 134 Pneumonia, Bronchiectasis, and Lung Abscess......Page 766 135 Pulmonary Thromboembolism and Deep-Vein Thrombosis......Page 775 136 Interstitial Lung Disease......Page 779 137 Diseases of the Pleura......Page 784 138 Diseases of the Mediastinum......Page 787 139 Disorders of Ventilation......Page 788 140 Sleep Apnea......Page 789 141 Acute Renal Failure......Page 792 142 Chronic Kidney Disease and Uremia......Page 797 143 Dialysis......Page 799 144 Renal Transplantation......Page 802 145 Glomerular Diseases......Page 805 146 Renal Tubular Disease......Page 814 147 Dysuria, Urinary Tract Infections, Bladder Pain, and Interstitial Cystitis......Page 821 148 Nephrolithiasis......Page 826 149 Urinary Tract Obstruction......Page 828 150 Peptic Ulcer and Related Disorders......Page 832 151 Inflammatory Bowel Diseases......Page 838 152 Colonic and Anorectal Diseases......Page 844 153 Cholelithiasis, Cholecystitis, and Cholangitis......Page 849 154 Pancreatitis......Page 856 155 Acute Hepatitis......Page 861 156 Chronic Hepatitis......Page 868 157 Cirrhosis and Alcoholic Liver Disease......Page 876 158 Portal Hypertension......Page 881 159 Diseases of Immediate-Type Hypersensitivity......Page 884 160 Primary Immune Deficiency Diseases......Page 889 161 Systemic Lupus Erythematosus......Page 892 162 Rheumatoid Arthritis......Page 894 163 The Spondyloarthritides......Page 896 164 Other Connective Tissue Diseases......Page 903 165 Vasculitis......Page 906 166 Osteoarthritis......Page 910 167 Gout, Pseudogout, and Related Diseases......Page 912 168 Other Musculoskeletal Disorders......Page 917 169 Sarcoidosis......Page 920 170 Amyloidosis......Page 922 171 Disorders of the Anterior Pituitary and Hypothalamus......Page 926 172 Diabetes Insipidus and Syndrome of Inappropriate Antidiuretic Hormone......Page 933 173 Thyroid Gland Disorders......Page 936 174 Adrenal Gland Disorders......Page 945 175 Obesity......Page 951 176 Diabetes Mellitus......Page 953 177 Disorders of the Male Reproductive System......Page 962 178 Disorders of the Female Reproductive System......Page 967 179 Hypercalcemia and Hypocalcemia......Page 976 180 Osteoporosis and Osteomalacia......Page 982 181 Hypercholesterolemia and Hypertriglyceridemia......Page 987 182 Hemochromatosis, Porphyrias, and Wilson’s Disease......Page 993 183 The Neurologic Examination......Page 1000 184 Seizures and Epilepsy......Page 1008 185 Alzheimer’s Disease and Other Dementias......Page 1020 186 Parkinson’s Disease......Page 1028 187 Ataxic Disorders......Page 1035 188 ALS and Other Motor Neuron Diseases......Page 1038 189 Autonomic Nervous System Disorders......Page 1041 190 Trigeminal Neuralgia, Bell’s Palsy, and Other Cranial Nerve Disorders......Page 1048 191 Spinal Cord Diseases......Page 1055 192 Multiple Sclerosis......Page 1061 193 Neuromyelitis Optica......Page 1069 194 Acute Meningitis and Encephalitis......Page 1072 195 Chronic and Recurrent Meningitis......Page 1084 196 Peripheral Neuropathies, Including Guillain-Barré Syndrome......Page 1094 197 Myasthenia Gravis......Page 1104 198 Muscle Diseases......Page 1107 199 Psychiatric Disorders......Page 1118 200 Psychiatric Medications......Page 1126 201 Eating Disorders......Page 1135 202 Alcohol Use Disorder......Page 1137 203 Narcotic Abuse......Page 1141 204 Cocaine and Other Commonly Used Drugs......Page 1143 205 Routine Disease Screening......Page 1148 206 Vaccines......Page 1152 207 Cardiovascular Disease Prevention......Page 1154 208 Prevention and Early Detection of Cancer......Page 1158 209 Smoking Cessation......Page 1165 210 Women’s Health......Page 1168 211 Adverse Drug Reactions......Page 1172 Index......Page 1185