Clinical Epidemiology of Chronic Liver Diseases

Description

This book emphasizes the clinical epidemiology of chronic liver diseases with a specific focus on the methodology of the discussed studies. The whole spectrum of liver diseases is covered, from chronic hepatitis B and C, to hepatocellular carcinoma, alcoholic and non-alcoholic fatty liver diseases and autoimmune and cholestatic liver diseases. Readers will find the most up-to-date information on clinical epidemiology of hepatology, and will also be able to learn about important methodology and biostatistics information. Each chapter contains a summary table at the end of each chapter that highlights the most relevant landmark studies, their main outcomes and the unique features of the methodology. The book will appeal to both practicing clinicians as well as clinical research investigators. In addition, this would likely be of interest to medical school or public health school students to learn about hepatology epidemiology, but also some specific fundamentals of clinical research and clinical epidemiology. Front Matter ....Pages i-viii Principles of Clinical Epidemiology (Rita Popat, Julia Simard)....Pages 1-15 Understanding Study Design for Clinical Epidemiology Studies (Jenny Krause Cohen, Irene H. Yen)....Pages 17-24 Understanding the Interpretation of Disease Incidence and Prevalence (Ehsan Chitsaz, Sheila Kumar)....Pages 25-31 Understanding Survival Analyses (Somasundaram Subramaniam)....Pages 33-39 Global Epidemiology of Chronic Liver Disease (Nimzing Gwamzhi Ladep, Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab)....Pages 41-55 Epidemiology of Chronic Liver Disease in the United States (Yihan Yang, Jeffrey Luk, Andre N. Sofair)....Pages 57-74 Epidemiology of Alcoholic Liver Disease (C. Taylor Richardson, Ashwani K. Singal)....Pages 75-98 Hepatitis B Virus: Asian Perspective (Wai-Kay Seto, Man-Fung Yuen)....Pages 99-116 Viral Hepatitis: The African Experience (Ramou Njie)....Pages 117-124 Hepatitis B: The Western Perspective (Elana Rosenthal, Rachel Baden)....Pages 125-134 Hepatitis D Virus (Mario Rizzetto)....Pages 135-148 Clinical Epidemiology of Hepatitis C Virus (Aparna Goel, Aijaz Ahmed, Imam Waked)....Pages 149-170 Enteric Hepatitis Viruses: Hepatitis A Virus and Hepatitis E Virus (Mohammad Sultan Khuroo, Mehnaaz S. Khuroo, Naira S. Khuroo)....Pages 171-209 Clinical Epidemiology of NAFLD (Donghee Kim, Osama Siddique, Brandon J. Perumpail, Aijaz Ahmed)....Pages 211-227 Clinical Epidemiology of Chronic Liver Disease: Hepatocellular Carcinoma (Duminda Suraweera, Peter Konyn, Thomas Vu, Sammy Saab)....Pages 229-249 Autoimmune Hepatitis and Immune-Mediated Cholestatic Liver Diseases (Albert J. Czaja)....Pages 251-305 The Epidemiology of Rare Hereditary Metabolic Liver Diseases (Marinos Pericleous, Claire Kelly, Aftab Ala, Michael L. Schilsky)....Pages 307-330 Cryptogenic Cirrhosis (Zachary Henry, Curtis K. Argo, Stephen H. Caldwell)....Pages 331-349