Fundamental Immunology

Description

Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover… • Fully revised and updated content reflects the latest advances in the field. • Current insights enhance readers’ understanding of immune system function • Unique approach bridges the gap between basic immunology and the disease process. • Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. • Abundant illustrations and tables deliver essential information at a glance. PLUS… A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today! Fundamental Immunology CONTRIBUTING AUTHORS PREFACE ACKNOWLEDGMENTS CONTENTS SECTION I Introduction to Immunology The Immune System History of Immunology SECTION II Organization and Evolution of the Lymphoid Tissues and Organs Evolution of the Immune System SECTION III Immunoglobulins and B Lymphocytes Immunoglobulins: Structure and Function Immunoglobulins: Molecular Genetics Antigen–Antibody Interactions and Monoclonal Antibodies B-Lymphocyte Development and Biology B-Lymphocyte Receptors, Signaling Mechanisms, and Activation B-Lymphocyte Responses SECTION IV T-Lymphocytes T-Cell Antigen Receptors Mechanisms of T-Lymphocyte Signaling and Activation T-Lymphocyte Developmental Biology Peripheral T Lymphocyte Responses and Function SECTION V The Intersection of Innate and Adaptive Immunity The Innate Immune System Dendritic Cells Natural Killer Cells CD1d–Restricted Natural Killer T Cells Macrophages and Phagocytosis Granulocytes and Mast Cells The Major Histocompatibility Complex and Its Proteins Antigen Processing and Presentation SECTION VI Induction, Regulation, and Effector Functions of the Immune Response Immunogenicity and Antigen Structure Fc Receptors and Their Role in Immune Regulation and Infl ammation Type I Cytokines and Interferons, and Their Receptors The Interleukin-1 Family Tumor Necrosis Factor–Related Cytokines in Immunity Chemokines Helper T-Cell Differentiation and Plasticity Programmed Cell Death Immunologic Memory Immunologic Tolerance Regulatory/Suppressor T Cells The Mucosal Immune System Neurophysiologic Refl ex Mechanisms in Immunology Complement Cell-Mediated Cytotoxicity SECTION VII Immunity to Infectious Agents The Immune Response to Parasites Immunity to Viruses Immunity to Intracellular Bacteria Immunity to Extracellular Bacteria Immunology of Human Immunodefi ciency Virus Infection Vaccines SECTION VIII Immunologic Mechanisms in Disease Autoimmunity and Autoimmune Diseases Immunologic Mechanisms of Allergic Disorders Transplantation Immunology Cancer Immunology Inborn Errors of Immunity INDEX REFERENCES CHAPTER 2 REFERENCES CHAPTER 3 REFERENCES CHAPTER 4 REFERENCES CHAPTER 5 REFERENCES CHAPTER 6 REFERENCES CHAPTER 7 REFERENCES CHAPTER 8 REFERENCES CHAPTER 9 REFERENCES CHAPTER 10 REFERENCES CHAPTER 11 REFERENCES CHAPTER 12 REFERENCES CHAPTER 13 REFERENCES CHAPTER 14 REFERENCES CHAPTER 15 REFERENCES CHAPTER 16 REFERENCES CHAPTER 17 REFERENCES CHAPTER 18 REFERENCES CHAPTER 19 REFERENCES CHAPTER 20 REFERENCES CHAPTER 21 REFERENCES CHAPTER 22 REFERENCES CHAPTER 23 REFERENCES CHAPTER 24 REFERENCES CHAPTER 25 REFERENCES CHAPTER 26 REFERENCES CHAPTER 27 REFERENCES CHAPTER 28 REFERENCES CHAPTER 29 REFERENCES CHAPTER 30 REFERENCES CHAPTER 31 REFERENCES CHAPTER 32 REFERENCES CHAPTER 33 REFERENCES CHAPTER 34 REFERENCES CHAPTER 35 REFERENCES CHAPTER 36 REFERENCES CHAPTER 37 REFERENCES CHAPTER 38 REFERENCES CHAPTER 39 REFERENCES CHAPTER 40 REFERENCES CHAPTER 41 REFERENCES CHAPTER 42 REFERENCES CHAPTER 43 REFERENCES CHAPTER 44 REFERENCES CHAPTER 45 REFERENCES CHAPTER 46 REFERENCES CHAPTER 47 REFERENCES CHAPTER 48 REFERENCES