New Therapeutic Agents in Thrombosis and Thrombolysis
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An essential text for cardiologists, hematologists, and pharmacologists, this third edition is a resource on current agent development technology for treating cardiovascular and thromboembolic diseases. It covers advances in scientific discovery, the growing number of patients and indications for antithrombotics, and more. Content: OVERVIEW OF THE INVESTIGATION AND REGULATION AND THROMBOSISJane EFreedmanOverview of Hemostasis and Fibrinolysis, Andrew ISchaferOverview of Platelet-Dependent Thrombosis, Jane EFreedman, Price Blair, and Joseph LoscalzoDesign Issues in Clinical Trials of Thrombolytic and Antithrombotic Agents, Robert PGiuglianoPharmacogenomics and Warfarin Anticoagulation, Melkon Hacobian and Samuel ZGoldhaberPharmacogenomics of Platelet Inhibitors, Srikanth Nagalla, Suzanne MLeal, and Paul FBrayThe Effects of Antiplatelet, Antithrombotic, and Thrombolytic Agents on Inflammation and Circulating Inflammatory Biomarkers, Erdal CavusogluThe Role of Platelet Function Testing in the Development of Platelet Inhibitors, Alan DMichelsonThe Role of Proteomics and Transcriptomics in the Development of Antithrombotics, Lisa Senzel, Dmitri VGnatenko, and Wadie FBahouNEW HEPARINS, THROMBIN INHIBITORS, AND ANTITHROMBOTICSJeffrey IWeitzOverview of New Anticoagulant Drugs, Nahid Qushmaq and Jeffrey IWeitzAnticoagulants for the Treatment of Venous Thromboembolism, Sam SchulmanAnticoagulation in Acute Coronary Syndromes, Simon JMcRae and John WEikelboomAnticoagulation in Pregnancy, Shannon MBatesAnticoagulants in Cancer, Edward NLibby and Agnes YLeeAnticoagulation in Children, Paul TMonagle and Anthony K.CChanNew Heparins: Synthetic Pentasaccharides, Pieter WKamphuisen and Harry RBullerTreatment of Heparin-Induced Thrombocytopenia, Theodore EWarkentinEmerging Links Between Thrombosis, Inflammation, and Angiogenesis: Key Role of Heparin and Low-Molecular-Weight Heparins, Shaker AMousaOral Direct Factor Xa Inhibitors, Alexander GGTurpieDirect Thrombin Inhibitors, Menaka Pai and Mark ACrowtherModulators of the Protein C Pathway, Charles TEsmonFactor IXa Inhibitors, Richard CBecker, Mark Chan, Emily LHoward, Kristian CDBecker, and Christopher PRusconiContact-Activation Pathways as Targets for New Anticoagulants, David Gailani, Thomas Renne', and Andras GruberNEW ANTIPLATELET AGENTSRobert PGiuglianoOverview of Antiplatelet Therapy, Shaker AMousa, James TWillerson, and Robert PGiuglianoMarkers of Platelet Function, Udaya STantry and Paul AGurbelIntravenous Glycoprotein IIb/IIIa Antagonists, Jason NKatz and Robert AHarringtonInhibitors of Platelet Adhesion: VWF-GPb/IX and Collagen-GPVIInhibitors, Robert GSchaubThree Generations of Thienopyridines: Ticlopidine, Clopidogrel, and Prasugrel, Stephen DWiviott and Elliott MAntmanDirect PYAntagonists, Marco CattaneoNitric Oxide Donors as Platelet Inhibitors, Lina Badimon and Gemma VilahurThe Interrelationship of Thrombin and Platelets-The Protease-Activated Receptor-, Rohit Bhatheja and David JMoliternoOther Antiplatelet Agents, Catherine McGorrian and Sonia SAnandThe Combination of Anticoagulants and Platelet Inhibitors Postcoronary Stent Implantation, Hussam Hamdalla and Steven RSteinhublNEW THROMBOLYTIC AGENTS AND INDICATIONSHRoger LijnenOverview of Established and New Thrombolytics, HRoger LijnenThrombolysis of Deep Vein Thrombosis, Peter Verhamme, Raymond Verhaeghe, and Geert MaleuxThrombolysis for Acute Pulmonary Embolism, Gregory Piazza and Samuel ZGoldhaberAcute Thrombolysis in Ischemic Cerebrovascular Disease, Gregory Jdel ZoppoFibrinolysis for Acute Myocardial Infarction, Cheuk-Kit Wong and Harvey DWhiteEpilogue: The Evolution of Therapeutic Management of Thrombotic and Cardiovascular Disease, Jane EFreedman and Joseph LoscalzoIndex
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