Essential Guide to Blood Coagulation, Second Edition

Description

Thrombotic and bleeding disorders affect at least 10 million people in the US alone. There has also been a great deal of concern over travel-related deep vein thrombosis and therefore much more interest and research into the field of blood clotting. This new and concise practical guide will cover all the essentials one needs to know when managing thrombotic and bleeding disorders. The field of haematology is undergoing major advances in thrombosis research, including significant additions to recommended treatment protocols. The Essential Guide to Coagulation will distil the most clinically, up-to-date and relevant material from the literature for all those working in the field.Faced with a bleeding patient, it may be difficult to discern whether blood loss is due to a local factor or secondary to an underlying haemostatic defect. There are a range of simple and specialized laboratory texts which can be performed to further define the cause of bleeding in a patient. Since the first edition there have been many developments in the field including many new anticoagulant drugs. These new classes of "direct thrombin inhibitors" slow the coagulation cascade by directly binding to thrombin, a clotting factor essential in the clotting process. If thrombin is blocked, clot formation is delayed. A key component of this guide will be the latest treatment strategies available for patients.Content: Chapter 1 Schematic presentation of the hemostatic system (pages 1–5): Nils EgbergChapter 2 Proposals for sampling instructions (pages 6–10): Margareta Blomback and Nils EgbergChapter 3 Laboratory investigations (pages 11–38): Jovan P. Antovic, Liselotte Onelov and Nils EgbergChapter 4 Hereditary bleeding disorders (pages 39–55): Margareta Holmstrom and Lars Goran LundbergChapter 5 Critical bleeding (pages 56–61): Maria Bruzelius, Anna Agren and Hans JohnssonChapter 6 Investigation of increased bleeding tendency (pages 62–67): Margareta Holmstrom and Lars Goran LundbergChapter 7 Venous thrombosis and pulmonary embolism (pages 69–93): Anders CarlssonChapter 8 Investigation of thromboembolic tendency (pages 94–96): Margareta HolmstromChapter 9 Heart disease (pages 97–104): Hakan Wallen and Rickard LinderChapter 10 Antiplatelet drug therapy and reversal of its effects (pages 105–110): Hakan Wallen, Hans Johnsson and Bo?Michael BellanderChapter 11 New oral anticoagulants: focus on currently approved oral factor Xa and thrombin inhibitors (pages 111–120): Rickard E. Malmstrom and Hans JohnssonChapter 12 Stroke and transient ischemic attack (pages 121–124): Nils Wahlgren and Mia von EulerChapter 13 Peripheral artery surgery (pages 125–126): Jesper SwedenborgChapter 14 Hemostasis in obstetrics and gynecology (pages 127–161): Katarina BremmeChapter 15 Hemostasis in children (pages 162–181): Susanna Ranta and Pia PetriniChapter 16 Emergency conditions associated with coagulation: DIC, HIT and TTP/HUS (pages 182–190): Jovan P. Antovic and Margareta Holmstrom