High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics

Description

This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend. Front Matter ....Pages i-xx Front Matter ....Pages 1-1 High-Resolution 3D Light Microscopy with STED and RESOLFT (Steffen J. Sahl, Stefan W. Hell)....Pages 3-32 Front Matter ....Pages 33-33 Scanning Laser Ophthalmoscopy (SLO) (Jörg Fischer, Tilman Otto, François Delori, Lucia Pace, Giovanni Staurenghi)....Pages 35-57 Optical Coherence Tomography (OCT): Principle and Technical Realization (Silke Aumann, Sabine Donner, Jörg Fischer, Frank Müller)....Pages 59-85 Ophthalmic Diagnostic Imaging: Retina (Philipp L. Müller, Sebastian Wolf, Rosa Dolz-Marco, Ali Tafreshi, Steffen Schmitz-Valckenberg, Frank G. Holz)....Pages 87-106 Ophthalmic Diagnostic Imaging: Glaucoma (Robert N. Weinreb, Christopher Bowd, Sasan Moghimi, Ali Tafreshi, Sebastian Rausch, Linda M. Zangwill)....Pages 107-134 OCT Angiography (OCTA) in Retinal Diagnostics (Roland Rocholz, Federico Corvi, Julian Weichsel, Stefan Schmidt, Giovanni Staurenghi)....Pages 135-160 OCT-Based Velocimetry for Blood Flow Quantification (Boy Braaf, Maximilian G. O. Gräfe, Néstor Uribe-Patarroyo, Brett E. Bouma, Benjamin J. Vakoc, Johannes F. de Boer et al.)....Pages 161-179 In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells (Dierck Hillmann, Clara Pfäffle, Hendrik Spahr, Helge Sudkamp, Gesa Franke, Gereon Hüttmann)....Pages 181-194 Two-Photon Scanning Laser Ophthalmoscope (Tschackad Kamali, Spring RM. Farrell, William H. Baldridge, Jörg Fischer, Balwantray C. Chauhan)....Pages 195-211 Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) (Paul Bernstein, Chantal Dysli, Jörg Fischer, Martin Hammer, Yoshihiko Katayama, Lydia Sauer et al.)....Pages 213-235 Selective Retina Therapy (Boris Považay, Ralf Brinkmann, Markus Stoller, Ralf Kessler)....Pages 237-259 Front Matter ....Pages 261-261 In Vivo Confocal Scanning Laser Microscopy (Oliver Stachs, Rudolf F. Guthoff, Silke Aumann)....Pages 263-284 Anterior Segment OCT (Jacqueline Sousa Asam, Melanie Polzer, Ali Tafreshi, Nino Hirnschall, Oliver Findl)....Pages 285-299 Femtosecond-Laser-Assisted Cataract Surgery (FLACS) (Hui Sun, Andreas Fritz, Gerit Dröge, Tobias Neuhann, Josef F. Bille)....Pages 301-317 Refractive Index Shaping: In Vivo Optimization of an Implanted Intraocular Lens (IOL) (Ruth Sahler, Josef F. Bille)....Pages 319-336 Front Matter ....Pages 337-337 The Development of Adaptive Optics and Its Application in Ophthalmology (Gopal Swamy Jayabalan, Josef F. Bille)....Pages 339-358 Adaptive Optics for Photoreceptor-Targeted Psychophysics (Wolf M. Harmening, Lawrence C. Sincich)....Pages 359-375 Compact Adaptive Optics Scanning Laser Ophthalmoscope with Phase Plates (Gopal Swamy Jayabalan, Ralf Kessler, Jörg Fischer, Josef F. Bille)....Pages 377-394 Back Matter ....Pages 395-407