Practical Aspects of Cosmetic Testing: How to Set up a Scientific Study in Skin Physiology

Description

Assessment of skin physiology is moving rapidly away from a purely descriptive approach as we gain a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as those relating to its barrier function and hydration. As a result of research utilizing bioengineering methods, reliable and reproducible approaches are now available for product testing in the pharmaceutical and cosmetic industry as well as in basic research. This book examines in detail all aspects of cosmetic testing – legal, general, and practical. After discussion of regulatory and ethical issues and guidelines, essential guidance is provided on the planning, performance, and evaluation of scientific studies in skin physiology. The topics addressed range from laboratory and staffing requirements through to testing devices and methods, factors influencing measurements, and study design. In addition, detailed information is provided on test settings for a range of cosmetic products. All of the authors are recognized experts in their field. This book will be invaluable to researchers, students, and medical staff in explaining how best to assess skin functions in controlled studies using non-invasive biophysical instruments. Front Matter....Pages i-xi Front Matter....Pages 1-1 Regulatory Aspects....Pages 3-13 Ethical Aspects of Cosmetic Testing....Pages 15-25 Good Clinical Practice....Pages 27-31 Guidelines in Dermocosmetic Testing....Pages 33-41 Claim Support: How to Create and Substantiate Claims....Pages 43-61 Front Matter....Pages 63-63 Testing Laboratory....Pages 65-73 Research Staff....Pages 75-77 Testing Population....Pages 79-82 Testing Devices and Methods....Pages 83-88 Factors Influencing Measurements....Pages 89-99 Study Design....Pages 101-106 Cosmetic Testing Report....Pages 107-119 Front Matter....Pages 121-121 Moisturizers and Emollients....Pages 123-141 Antiaging and Antiwrinkle Products....Pages 143-153 Products for Impure, Acne-Like Skin....Pages 155-170 Assessment of Hair Morphology....Pages 171-178 Skin Colour and Pigmentation....Pages 179-185 Characterization of Sunscreens: Determination of the SPF....Pages 187-195 Practical Aspects of Shampoo and Conditioner Testing....Pages 197-215 Antiperspirants and Deodorants....Pages 217-226 Front Matter....Pages 121-121 Hair Growth....Pages 227-245 Sensory Perception....Pages 247-252 Practical Use and Significance of Transepidermal Water Loss Measurements....Pages 253-259 Compliance Check with On-Site Measurements: Advanced Ways in Product Testing....Pages 261-265 Back Matter....Pages 267-272