Novel Optical Resolution Technologies

Description

G. Coquerel: Preferential Crystallization.- R. Tamura, H. Takahashi, D. Fujimoto, T. Ushio: Mechanism and Scope of Preferential Enrichment, a Symmetry-Breaking Enantiomeric Resolution Phenomenon.- R. Yoshioka: Racemization, Optical Resolution, and Crystallization-Induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates.- F. Faigl, J. Schindler, E. Fogassy: Advantages of Structural Similarities of the Reactants in Optical Resolution Processes.- R.M. Kellogg , B. Kaptein, T.R. Vries: Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition.- K. Sakai, R. Sakurai, H. Nohira: New Resolution Technologies Controlled by Chiral Discrimination Mechanisms.- K. Sakai, R. Sakurai, N. Hirayama: Molecular Mechanisms of Dielectrically Controlled Resolution (DCR).- H. Murakami: From Racemates to Single Enantiomers – Chiral Synthetic Drugs over the Recent 20 Years Front Matter....Pages I-XIV Preferential Crystallization....Pages 1-51 Mechanism and Scope of Preferential Enrichment, a Symmetry-Breaking Enantiomeric Resolution Phenomenon....Pages 53-82 Racemization, Optical Resolution and Crystallization-Induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates....Pages 83-132 Advantages of Structural Similaritiesof the Reactants in Optical Resolution Processes....Pages 133-157 Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition....Pages 159-197 New Resolution Technologies Controlled by Chiral Discrimination Mechanisms....Pages 199-231 Molecular Mechanisms of Dielectrically Controlled Resolution (DCR)....Pages 233-271 From Racemates to Single Enantiomers – Chiral Synthetic Drugs over the last 20 Years....Pages 273-299 Back Matter....Pages 301-313