Antidiabetic Potential of Plants in the Era of Omics

Description

Here is an informative overview of diabetes mellitus in conjunction with plant-based treatments. It discusses available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches. The book begins with an introduction to diabetes, giving a brief overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with ethnobotanical information. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects of active plantbased antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques. Cover Half Title Title Copyright About the Editors Contents Contributors Abbreviations Preface Part I: Introduction of Metabolic Disorder Diabetes 1. Diabetes Mellitus: History, Diagnosis, Classification, Pathophysiology, and Risk Factors 2. Diabetes Mellitus: Signs and Symptoms, Epidemiology, Current Prevention, Management Therapies, and Treatments Part II: Antidiabetic Plants in Systems of Traditional Knowledge 3. The ‘Green Healers’ of Diabetes Mellitus: An Ayurvedic Eye 4. Concept of Diabetes Mellitus and Antidiabetic Plant in the Unani System of Medicine 5. Omics Technology in Antidiabetic Plant Research 6. Ethnobotanical Information of Medicinal Plants Used for Diabetes Mellitus in Seshachalam Biosphere Reserve, Andhra Pradesh, India Part III: Mode of Action 7. Overview of Steviol Glycosides: Action Toward Diabetes Control 8. Mechanism of Action of the Traditional and Modern Phyto-Biotics in the Treatment of Diabetes in the Current Era 9. Molecular Insights of Active Plant-Based Antidiabetic Drug Molecules Part IV: Recent Biotechnological Advancements of Antidiabetic Plants and Plant-Based Anti-Diabetes Drugs and Future Perspectives with Genome Editing Technologies 10. Molecular Breeding and Application of Molecular Markers for Improvement of Antidiabetic Medicinal Plants 11. Biotechnologically Engineered Transgenic Medicinal Plants: Exploration of Antidiabetic Properties 12. Transcriptomic Studies of Medicinal Plants Elucidating Their Role in Diabetes 13. How Metabolomics Shapes the Future of Drugs in Antidiabetic Plants 14. Zinc Finger Nuclease Based Genome Editing in Enhancement of Antidiabetic Activity of Plants: Prospective Applications 15. Transcription Activator-Like Effector Nucleases (TALENs): Genome Editing Tool to Explore Enhanced Activity of Antidiabetic Plants Index