Transport Across Natural and Modified Biological Membranes and its Implications in Physiology and Therapy

Description

This book elucidates the mechanisms involved in biological membrane functions. It describes the new modalities and characterization for basic in vitro as well as computer models of biological membranes. Biological membranes are analyzed in terms of advances in molecular dynamics. The individual chapters provide an in depth analysis of images from various biological models. The potential of membrane models in the context of treatment trials is discussed. The authors present new insights and current concepts for treatment procedures (nanocarriers, electroporation, channel blockers). Front Matter ....Pages i-ix Atomistic Simulations of Electroporation of Model Cell Membranes (Mounir Tarek)....Pages 1-15 Role of Bioinformatics in the Study of Ionic Channels (Monika Kurczyńska, Bogumił M. Konopka, Małgorzata Kotulska)....Pages 17-37 Cell Membrane Transport Mechanisms: Ion Channels and Electrical Properties of Cell Membranes (Julita Kulbacka, Anna Choromańska, Joanna Rossowska, Joanna Weżgowiec, Jolanta Saczko, Marie-Pierre Rols)....Pages 39-58 Cell Membrane Electropulsation: Chemical Analysis of Cell Membrane Modifications and Associated Transport Mechanisms (Antoine Azan, Florian Gailliègue, Lluis M. Mir, Marie Breton)....Pages 59-71 Physical Methods for Drug and Gene Delivery Through the Cell Plasma Membrane (Milda Jakutavičiūtė, Paulius Ruzgys, Mindaugas Tamošiūnas, Martynas Maciulevičius, Saulius Šatkauskas)....Pages 73-92 Estrogen Receptors in Cell Membranes: Regulation and Signaling (Jolanta Saczko, Olga Michel, Agnieszka Chwiłkowska, Ewa Sawicka, Justyna Mączyńska, Julita Kulbacka)....Pages 93-105 How Imaging Membrane and Cell Processes Involved in Electropermeabilization Can Improve Its Development in Cell Biology and in Clinics (Laure Gibot, Muriel Golzio, Marie-Pierre Rols)....Pages 107-118 Analysis, Recognition, and Classification of Biological Membrane Images (Marek Kulbacki, Jakub Segen, Artur Bak)....Pages 119-140