Somatic Cell Genetics

Description

Front Matter....Pages i-viii Pathway Mutants in Mammalian Cells and Their Contribution to the Analysis of Drug Resistance....Pages 1-17 Isolation and Analysis of Chinese Hamster Cells Carrying Forward and Reverse Mutations in the Hypoxanthine-Guanine Phosphoribosyltransferase Locus....Pages 19-41 Towards Mapping Genes to Chromosomes Using Two Dimensional Gel Electrophoresis of Proteins and Somatic Cell Hybridization. Preliminary Studies....Pages 43-54 The Use of Mouse-Human and Human-Human Hybridomas in Human Genetics and Immunology....Pages 55-68 Expression of Liver Mono-Oxygenase Functions Induced by Xenobiotics....Pages 69-85 Gene Mapping and Gene Transfer in Mammalian Cells....Pages 87-95 Dihydrofolate Reductase Gene Amplification, Altered Dihydrofolate Reductase, and Methotrexate Resistance in Cultured 3T6 Cells Associated with Unstable Amplification of an Altered Dihydrofolate Reductase Gene....Pages 97-109 Transformation and Expression of TK Sequences....Pages 111-125 Genetic Variants of Cultured Animal Cells....Pages 127-167 Cell Hybridization: A Tool for the Study of Cell Differentiation....Pages 169-182 Use of Somatic Cell Hybridization and DNA-Mediated Gene Transfer for Characterization of Neoplastic Transformation....Pages 183-195 Analysis of Cell Surface Antigens with Monoclonal Antibodies....Pages 197-212 Back Matter....Pages 213-218