ENGLISH

Cytokine Storm Syndrome

By Randy Q. Cron , Edward M. Behrens

Book information

Publisher
Springer International Publishing
Year
2019
ISBN
978-3-030-22093-8, 978-3-030-22094-5
Language
english
Format
PDF
Filesize
10 MB (11007985 bytes)
Edition
1st ed. 2019
Pages
XXI, 617\607
Time added
2020-02-08 04:41:16
Biomedicine; Immunology; Cytogenetics; Infectious

Description

Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals. A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment. Front Matter ....Pages i-xxi Front Matter ....Pages 1-1 History of Hemophagocytic Lymphohistiocytosis (Gritta E. Janka)....Pages 3-16 The History of Macrophage Activation Syndrome in Autoimmune Diseases (Earl D. Silverman)....Pages 17-29 Clinical Features of Cytokine Storm Syndrome (Masaki Shimizu)....Pages 31-41 Laboratory Features and Pathology of the Cytokine Storm Syndromes (Flavia G. Rosado, Purva Gopal)....Pages 43-59 Criteria for Cytokine Storm Syndromes (Francesca Minoia, Sergio Davì, Alessandra Alongi, Angelo Ravelli)....Pages 61-79 Front Matter ....Pages 81-81 Genetics of Primary Hemophagocytic Lymphohistiocytosis (Spyridon Karageorgos, Hamid Bassiri)....Pages 83-111 Genetics of Acquired Cytokine Storm Syndromes (Grant S. Schulert, Kejian Zhang)....Pages 113-129 Genetics of Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis (Alexei A. Grom)....Pages 131-138 Front Matter ....Pages 139-139 CD8+ T Cell Biology in Cytokine Storm Syndromes (Takuya Sekine, Donatella Galgano, Giovanna P. Casoni, Marie Meeths, Yenan T. Bryceson)....Pages 141-161 Immunology of Cytokine Storm Syndromes: Natural Killer Cells (Anthony R. French, Megan A. Cooper)....Pages 163-181 Myeloid Cells in the Immunopathogenesis of Cytokine Storm Syndromes (Lehn K. Weaver)....Pages 183-195 Cytokines in Cytokine Storm Syndrome (Edward M. Behrens)....Pages 197-207 Primary Immunodeficiencies and Cytokine Storm Syndromes (David A. Hill, Neil Romberg)....Pages 209-232 Front Matter ....Pages 233-233 Infectious Triggers of Cytokine Storm Syndromes: Herpes Virus Family (Non-EBV) (Daniel Dulek, Isaac Thomsen)....Pages 235-252 Cytokine Storm Syndromes Associated with Epstein–Barr Virus (Katherine C. Verbist, Kim E. Nichols)....Pages 253-276 Cytokine Storm Syndrome Associated with Hemorrhagic Fever and Other Viruses (Ethan S. Sen, A. V. Ramanan)....Pages 277-297 Cytokine Storm Syndrome as a Manifestation of Primary HIV Infection (Nathan Erdmann, Sonya L. Heath)....Pages 299-306 Bacteria-Associated Cytokine Storm Syndrome (Esraa M. Eloseily, Randy Q. Cron)....Pages 307-317 Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome (Zaher K. Otrock, Charles S. Eby)....Pages 319-330 Parasitic and Fungal Triggers (Gary Sterba, Yonit Sterba)....Pages 331-345 Front Matter ....Pages 347-347 Cytokine Storm Syndrome Associated with Systemic Juvenile Idiopathic Arthritis (Rayfel Schneider, Susan P. Canny, Elizabeth D. Mellins)....Pages 349-379 Systemic Lupus Erythematosus and Cytokine Storm (Roberto Caricchio)....Pages 381-392 Kawasaki Disease-Associated Cytokine Storm Syndrome (Rolando Ulloa-Gutierrez, Martin Prince Alphonse, Anita Dhanranjani, Rae S. M. Yeung)....Pages 393-406 The Intersections of Autoinflammation and Cytokine Storm (Scott W. Canna)....Pages 407-421 Macrophage Activation Syndrome in the Setting of Rheumatic Diseases (W. Winn Chatham)....Pages 423-434 Front Matter ....Pages 435-435 Hemophagocytic Lymphohistiocytosis in the Context of Hematological Malignancies and Solid Tumors (Kai Lehmberg)....Pages 437-449 Cytokine Storm and Sepsis-Induced Multiple Organ Dysfunction Syndrome (Joseph A. Carcillo, Bita Shakoory)....Pages 451-464 Front Matter ....Pages 465-465 Murine Models of Familial Cytokine Storm Syndromes (Benjamin Volkmer, Peter Aichele, Jana Pachlopnik Schmid)....Pages 467-489 Murine Models of Secondary Cytokine Storm Syndromes (Ellen Brisse, Carine H. Wouters, Patrick Matthys)....Pages 491-518 Front Matter ....Pages 519-519 Etoposide Therapy of Cytokine Storm Syndromes (Jan-Inge Henter, Tatiana von Bahr Greenwood)....Pages 521-547 IL-1 Family Blockade in Cytokine Storm Syndromes (Randy Q. Cron)....Pages 549-559 IL-6 Blockade in Cytokine Storm Syndromes (David Barrett)....Pages 561-568 Anti-interferon-γ Therapy for Cytokine Storm Syndromes (Fabrizio De Benedetti)....Pages 569-580 Alternative Therapies for Cytokine Storm Syndromes (Seza Ozen, Saliha Esenboga)....Pages 581-593 Salvage Therapy and Allogeneic Hematopoietic Cell Transplantation for the Severe Cytokine Storm Syndrome of Hemophagocytic Lymphohistiocytosis (Rebecca A. Marsh)....Pages 595-606 Back Matter ....Pages 607-617

Similar books

Session C11: Ancient Cultural Landscapes in South Europe – their Ecological Setting and Evolution, Session C22: Gardeners from South America, Session S04: Agro-Pastoralism and Early Metallurgy Sessions, Session WS29: The Idea of Enclosure in Recent Iberian Prehistory, Session C88: Rhytmes et causalites des dynamiques de l'anthropisation en Europe entre 6500 ET 500 BC: Hypotheses socio-culturelles et/ou climatiques: Proceedings of the XV UISPP World Congress (Lisbon 4-9 September 2006) / Actes du XV Congrès Mondial (Lisbonne 4-9 Septembre 2006) Vol.36

Session C11: Ancient Cultural Landscapes in South Europe – their Ecological Setting and Evolution, Session C22: Gardeners from South America, Session S04: Agro-Pastoralism and Early Metallurgy Sessions, Session WS29: The Idea of Enclosure in Recent Iberian Prehistory, Session C88: Rhytmes et causalites des dynamiques de l'anthropisation en Europe entre 6500 ET 500 BC: Hypotheses socio-culturelles et/ou climatiques: Proceedings of the XV UISPP World Congress (Lisbon 4-9 September 2006) / Actes du XV Congrès Mondial (Lisbonne 4-9 Septembre 2006) Vol.36

2010 · PDF

THE BRITISH ARMY IN INDIA: ITS PRESERVATION BY AN APPROPRIATE CLOTHING, HOUSING, LOCATING, RECREATIVE EMPLOYMENT, AND HOPEFUL ENCOURAGEMENT OF THE TROOPS. with AN APPENDIX ON INDIA : THE CLIMATE OP ITS HILLS ; THE DEVELOPMENT OF ITS RESODRCBS, INDUSTRY, AND ARTS ; THE ADMINISTRATION OF JUSTICE ; THE BLACK ACT ; THE PROGRESS OF CHRISTIANITY ; THE TRAFFIC IN OPIUM ; THE VALUE OF INDIA ; PERMANENT CAUSES OF DISAFFECTION, AND OF THE RECENT REBELLION ; THE TRADITIONARY POLICY; MISGOVERNMENT BY NATIVE RULERS ; ANNEXATIONS OF THEIR TERRITORY, ETC.

THE BRITISH ARMY IN INDIA: ITS PRESERVATION BY AN APPROPRIATE CLOTHING, HOUSING, LOCATING, RECREATIVE EMPLOYMENT, AND HOPEFUL ENCOURAGEMENT OF THE TROOPS. with AN APPENDIX ON INDIA : THE CLIMATE OP ITS HILLS ; THE DEVELOPMENT OF ITS RESODRCBS, INDUSTRY, AND ARTS ; THE ADMINISTRATION OF JUSTICE ; THE BLACK ACT ; THE PROGRESS OF CHRISTIANITY ; THE TRAFFIC IN OPIUM ; THE VALUE OF INDIA ; PERMANENT CAUSES OF DISAFFECTION, AND OF THE RECENT REBELLION ; THE TRADITIONARY POLICY; MISGOVERNMENT BY NATIVE RULERS ; ANNEXATIONS OF THEIR TERRITORY, ETC.

1858 · PDF

Idries Shah 27 Books Collection : A Perfumed Scorpion, A Veiled Gazelle, Caravan of Dreams, Darkest England, Destination Mecca, Evenings with Idries Shah, Knowing How to Know, Learning How to Learn, Letters and Lectures of Idries Shah, Neglected aspects of Sufi study, Observations, Oriental Magic, Reflections, Seeker after Truth, Special Illumination, Special Problems in the study of Sufi ideas, Sufi thought and action, Tales of the Dervishes, The Dermis Probe, The Elephant in the Dark, The Englishman Handbook, Idries Shah Antology, The Magic Monastery, The natives are restless, wisdom of the Idiots PDF.

Idries Shah 27 Books Collection : A Perfumed Scorpion, A Veiled Gazelle, Caravan of Dreams, Darkest England, Destination Mecca, Evenings with Idries Shah, Knowing How to Know, Learning How to Learn, Letters and Lectures of Idries Shah, Neglected aspects of Sufi study, Observations, Oriental Magic, Reflections, Seeker after Truth, Special Illumination, Special Problems in the study of Sufi ideas, Sufi thought and action, Tales of the Dervishes, The Dermis Probe, The Elephant in the Dark, The Englishman Handbook, Idries Shah Antology, The Magic Monastery, The natives are restless, wisdom of the Idiots PDF.

2022 · PDF

The travels of Capts. Lewis and Clarke from St. Louis, by way of the Missouri and Columbia rivers, to the Pacific ocean; performed in the years 1804, 1805 & 1806, by order of the government of the United States. Containing delineations of the manners, customs, religion, &c. of the Indians, comp. from various authentic sources, and original documents, and a summary of the Statistical view of the Indian nations, from the official communication of Meriwether Lewis. Illustrated with a map of the country, inhabited by the western tribes of Indians

The travels of Capts. Lewis and Clarke from St. Louis, by way of the Missouri and Columbia rivers, to the Pacific ocean; performed in the years 1804, 1805 & 1806, by order of the government of the United States. Containing delineations of the manners, customs, religion, &c. of the Indians, comp. from various authentic sources, and original documents, and a summary of the Statistical view of the Indian nations, from the official communication of Meriwether Lewis. Illustrated with a map of the country, inhabited by the western tribes of Indians

1809 · PDF

Professional Linux kernel architecture ''Wrox programmer to programmer''--Cover. - ''What you are reading right now is the result of an evolution over more than seven years: After two years of writing, the first edition was published in German by Carl Hanser Verlag in 2003. It then described kernel 2.6.0. The test was used as a basis for the low-level design documentation for the EAL4+ security evaluation of Red Hat Enterprise Linux 5, requiring to update it to kernel 2.6.18 (if the EAL acronym does not mean anything to you, then Wikipedia is once more your friend). Hewlett-Packard sponsored the translation into English and has, thankfully, granted the rights to publish the result. Updates to kernel 2.6.24 were then performed specifically for this book''--P. ix

Professional Linux kernel architecture ''Wrox programmer to programmer''--Cover. - ''What you are reading right now is the result of an evolution over more than seven years: After two years of writing, the first edition was published in German by Carl Hanser Verlag in 2003. It then described kernel 2.6.0. The test was used as a basis for the low-level design documentation for the EAL4+ security evaluation of Red Hat Enterprise Linux 5, requiring to update it to kernel 2.6.18 (if the EAL acronym does not mean anything to you, then Wikipedia is once more your friend). Hewlett-Packard sponsored the translation into English and has, thankfully, granted the rights to publish the result. Updates to kernel 2.6.24 were then performed specifically for this book''--P. ix

2008 · PDF