ENGLISH

Emerging Chagas disease

By António Teixeira , Marina Vinaud , Ana Maria Castro

Book information

Publisher
Bentham Science Publishers
Year
2011
ISBN
9781608050413
DOI
10.2174/97816080504131090101
Language
english
Format
PDF
Filesize
15 MB (15449750 bytes)
Pages
191\191
Time added
2014-06-22 18:42:10

Description

The book focuses on a global problem challenging the health systems. Trypanosoma cruzi infections are transmitted by cone-nosed triatomine bugs, by blood transfusion and congenitally from mothers to their offspring. the American Trypanosomiasis affects 20 million people; among them a significant parcel (< 1/3) will develop Chagas disease in the heart and digestive tract, where the immune system effector cells destroy target host cells. Genotype modifications resulting from transfer of minicircle sequence kDNA from the parasite into the host's genome may explain the autoimmune pathogenesis of the disease. the book discusses various aspects of this disease and should be of interest to readers who wish to keep abreast of the developments in this field.

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