ENGLISH

Adenoviruses: Basic Biology to Gene Therapy

By Prem Seth

Book information

Publisher
Landes Bioscience
Year
1999
ISBN
1-57059-584-4, 9781570595844
LCC
QR396 .A343 1999
Open Library ID
OL41127M
Language
english
Format
DJVU
Filesize
4 MB (3952914 bytes)
Series
Medical Intelligence Unit 15
Edition
1
Pages
314\333
Topic
Medicine Therapy
Library
ihtik
Time added
2009-07-20 05:12:22

Description

Ever since their discovery, adenoviruses have proven to be tremendous asset to biologists. Through the study of the adenoviruses the authors have learned not only about the virus structures, mechanisms of viral replication, but also about eukaryotic gene expression, alternative splicing, regulation of cell cycle progression, and apoptosis. In the last five years, there has been an explosion in the use of adenoviruses as vectors for gene transfer to a variety of mammalian cells. Adenoviral vectors are also being tested in Phase I clinical trials for cystic fibrosis and for many kinds of cancers. These recent developments in utilizing adenoviral vectors for gene therapy have rejuvenate an interest in the basic science of adenovirus research. More importantly, it has generated a necessity for a single volume that covers both the biology of adenoviruses as well as our progress in the use of adenoviruses as vectors for gene therapy. This book was written precisely to fulfill such a need.

Similar books