Probing Bioactive Mechanisms

Description

Content: Progress in the design of bioactive molecules / John H. Block -- Predicting mechanism and activity / Douglas R. Henry -- Interfacing statistics, quantum chemistry, and molecular modeling / Philip S. Magee -- Second-generation computer-assisted inhibitor design method / Renee L. DesJarlais, George L. Seibel, Irwin D. Kuntz -- Statistical modeling of molecular shape, similarity, and mechanism / Douglas R. Henry, A. Morrie Craig -- New tool for the study of structure, activity relationships in three dimensions / Arthur M. Doweyko -- Finding lead structures from amino acid sequence similarities of target proteins / Takaaki Nishioka, Kazuo Sumi, Jun'ichi Oda -- Application of micellar liquid chromatography to modeling of organic compounds by quantitative structure / Barry K. Lavine ... [et al.] -- Inhibition of susceptible and resistant green rice leafhopper acetylcholinesterase by N-Methylcarbamate and oxadiazolone insectides / Hiroki Ohta ... [et al.] -- Critical differences in the binding of aryl phosphate and carbamate inhibitors of acetylcholinesterases / Philip S. Magee -- Contribution of quantitative agrochemical design strategies to mechanism-of-action studies / E.L. Plummer, J.A. Dixson, R.M. Kral -- Quantitative structure, activity relationship study of aromatic trifluoromethyl ketones / András Székács ... [et al.] -- Conformational analysis of fenvalerate and an ether-type pyrethroid / Yasuyuki Kurita, Kazunori Tsushima, Chiyozo Takayama -- Molecular design and target site analysis in fungicide development / Hugh D. Sisler, Nancy N. Ragsdale -- Modeling of photosystem II inhibitors of the herbicide-binding protein / W. Draber, B. Pittel, A. Trebst -- A₁ adenosine receptors in the heart / T.F. Murray ... [et al.] -- Therapeutic potential for parathyroid hormone antagonist / Mark E. Goldman, Michael Rosenblatt -- Interaction of phenylisopropylamines with central 5-HT2 receptors / Richard A. Glennon, Mark R. Seggel -- Analysis of binding at 4-aminobutyric acid receptor sites by structure-activity relationships / Philip S. Magee, James W. King -- Quantitative structure-activity relationships for the cytotoxicity of substituted aniline mustards in tissue culture / William A. Denny, William R. Wilson, Brian D. Palmer -- Quantitative structure-activity relationships of antibacterial compounds based on the nalidixic acid structure / John H. Block ... [et al.] -- Structurally specific interaction of halogenated dioxin and biphenyl derivatives with iodothyronine-5-́deiodinase in rat liver / U. Rickenbacher, S. Jordan, J.D. McKinney -- Base-line toxicity predicted by quantitative structure-activity relationships as a probe for molecular mechanism of toxicity / Robert L. Lipnick -- Correlations and mechanisms of chemical toxicity in animals / Philip S. Magee, James W. King.