Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach
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Description
Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth. Front Matter ....Pages i-xviii Cancer Biology and Its Treatment Modalities: A Brief Historical Perspective (Aasna L. Parui, Kakoli Bose)....Pages 1-11 Emerging Peptide-Based Technologies in Cancer Therapy (Argha Mario Mallick, Kasturee Chakraborty, Abhijit Biswas, Somnath Jan, Chiranjit Dutta, Souvik Dey et al.)....Pages 13-49 Protein Palmitoylation in Cancer (Sonia Lobo)....Pages 51-87 Advances in Mass Spectrometry-Based Proteomics and Its Application in Cancer Research (Markus Hardt)....Pages 89-112 Apoptosis in Cancer Cell Signaling and Current Therapeutic Possibilities (Ajay R. Wagh, Kakoli Bose)....Pages 113-129 Integration of Evolutionary Theory into Cancer Biology and Caspase Signaling (Robert D. Grinshpon, A. Clay Clark)....Pages 131-155 Emerging Epigenetic Targets and Their Implications in Cancer Therapy (Mohmmad Shoab Mansuri, Sonam Mehrotra)....Pages 157-188 Anticancer Immunotherapy: Prospects and Challenges (Ruchi Sachdeva, Poonam Singh, Anjali Bose, Beneeta Kalha, Moumita Sarkar, Rahul Pal)....Pages 189-228 Preclinical Animal Models for Cancer Research and Drug Discovery (Akshay Dhumal, Kiran Bendale, Pradip Chaudhari)....Pages 229-254 Dysregulated Signaling Pathways in Cancer: Approaches and Applications (Pranay Ramteke, Dipti Athavale, Manoj Kumar Bhat)....Pages 255-269 Analysing Cancer Signalling Pathways: A Structural Bioinformatics Approach (Jitesh Doshi, Shubhankar Dutta, Kakoli Bose)....Pages 271-293 Targeting Cancer from a Structural Biology Perspective (Derion Reid, Carla Mattos)....Pages 295-320 Applications of NMR in Cancer Research (James D. Baleja, Tiffany Corlin, Athan Kuliopulos, Addy Alt-Holland)....Pages 321-341 Proteomics for Cancer: Approaches and Challenges (Surekha M. Zingde)....Pages 343-368 Applications of Microarray in Cancer Cell Signaling Pathways (Pak Ling Lui, Tae-Hoon Chung, Wee Joo Chng)....Pages 369-387 Nanotechnology: The Future for Cancer Treatment (Yogita Patil-Sen, Ashwin Narain, Simran Asawa, Tanvi Tavarna)....Pages 389-418 Preclinical Non-invasive Imaging in Cancer Research and Drug Discovery: An Overview (Pardeep Kumar, Baljinder Singh, Pradip Chaudhari, Jithin Jose, Anthony Butler, Hannah Prebble et al.)....Pages 419-469 Genomic Applications and Insights in Unravelling Cancer Signalling Pathways (Megha Lal, Deepanjan Paul, Subhashree Nayak, Arijit Mukhopadhyay)....Pages 471-511 Applications of Computational Systems Biology in Cancer Signaling Pathways (Vandana Sandhu, Venkata Satya Kumar Manem, Arvind Singh Mer, Elin H. Kure, Benjamin Haibe-Kains)....Pages 513-537 New Emerging Molecules in Cancer Research Which Hold Promise in Current Era (Dimple R. Bhatia, Sushmita Rath, Sudeep Gupta)....Pages 539-583
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