ENGLISH

Regulatory Peptides and Cognate Receptors

By Mark G. Darlison , Dietmar Richter (auth.) , Professor Dr. Dietmar Richter (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
1999
ISBN
978-3-662-12908-1, 978-3-540-49421-8
DOI
10.1007/978-3-540-49421-8
Language
english
Format
PDF
Filesize
15 MB (15398699 bytes)
Series
Results and Problems in Cell Differentiation 26
Edition
1
Pages
366\370
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Cell Biology; Biochemistrygeneral; Neurosciences; Human Physiology; Animal P

Description

In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro". Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a familiy of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.

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