ENGLISH

Fibrinolytics and Antifibrinolytics

By F. Bachmann (auth.) , Professor emeritus F. Bachmann (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2001
ISBN
978-3-642-63029-3, 978-3-642-56637-0
DOI
10.1007/978-3-642-56637-0
Language
english
Format
PDF
Filesize
13 MB (13891330 bytes)
Series
Handbook of Experimental Pharmacology 146
Edition
1
Pages
599\613
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
general; CardiologyPharmacology/Toxicology; Biochemistry

Description

This book covers basic aspects of the molecular biology, biochemistry and pharmacology of the plasminogen-plasmin (fibrinolytic) system. Individual chapters, written by well-known experts in the field, are devoted to plasminogen and its activation, the tissue-type plasminogen activator (tPA), the urinary-type-plasminogen activator (uPA), inhibitors of the fibrinolytic system, and the assembly of fibrinolytic constituents on cell surfaces. The major part of the book deals with the therapeutic use of thrombolytic agents in myocardial infarction, deep venous thrombosis, pulmonary embolism, peripheral arterial occlusions and stroke. The newest thrombolytic agents are discussed in depth. Results of major clinical trials up to the end of 1999 are critically evaluated. The volume is a modern up-to-date presentation of the entire field of the treatment of arterial and venous thromboses with thrombolytic agents.

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