ENGLISH

Bone Metastasis: Experimental and Clinical Therapeutics (Cancer Drug Discovery and Development)

By Gurmit Singh , Shafaat A. Rabbani

Book information

Publisher
Humana Press
Year
2005
ISBN
158829403X, 9781588294036
Open Library ID
OL18223004M
Language
english
Format
PDF
Filesize
5 MB (5236155 bytes)
Edition
1
Pages
360\343
Topic
Medicine Oncology
Time added
2011-06-04 13:46:07

Description

A state-of-the-art review of the molecular underpinnings of bone-seeking cancers, current treatment approaches for them, and future therapeutic strategies. The authors illuminate the role of various autocrine, paracrine, and immunological factors involved in the progression and establishment of bone metastases, highlighting the physiological processes that lead to bone degradation, pain, angiogenesis, and dysregulation of bone turnover. They also discuss the various strategies that appear to have promise and are currently deployed in treatment or are at the experimental stage.

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