ENGLISH

Innate Immunity

By Philippe Georgel , Xin Du , Kasper Hoebe , Bruce Beutler (auth.) , Jonathan Ewbank , Eric Vivier (eds.)

Book information

Publisher
Humana Press
Year
2008
ISBN
9781588297464, 1588297462
DOI
10.1007/978-1-59745-570-1
Open Library ID
OL12325720M
Language
english
Format
PDF
Filesize
9 MB (9087645 bytes)
Series
Methods in Molecular Biology 415
Edition
1
Pages
458\452
Topic
Biology
Library
avaxhome.ws
Time added
2010-05-31 14:30:26
Immunology; Cell Biology; Human Genetics; Molecula

Description

Immunologists today are interested in all of the diverse cell-types involved in host defense and have a deeper appreciation of the importance of innate immune mechanisms as a first line of protection against pathogens. This volume thus discusses the isolation and functional characterization of cells involved in innate immunity in mouse and man, including mast cells and eosinophils. Other focuses include natural killer cells, methods in statistics, in vivo imaging, genome engineering, and mutagenesis and culture that are adapted to the study of innate immunity in these hosts. These are complemented with a series of chapters dealing with alternative models: plants, worms, mosquitoes, flies, and fish. Together, these approaches and models are being used to dissect the complex interplay between hosts and pathogens and contribute to developing strategies to help fight infection. With chapters written by experts on the cutting-edge of this technology, Innate Immunity is an essential reference for immunologists, histologists, geneticists, and molecular biologists.

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