ENGLISH

Hypertension: Methods and Protocols (Methods in Molecular Medicine)

By Andrew H. Baker , Jerome P. Fennell

Book information

Year
2004
ISBN
9781588293237, 9781592598502, 1588293238
LCC
RC685.H8 H855 2005
Open Library ID
OL21802293M
Language
english
Format
PDF
Filesize
9 MB (9753178 bytes)
Edition
1
Pages
520\501
Time added
2011-06-04 13:46:07

Description

A collection of new and essential molecular techniques for cardiovascular research. These readily reproducible methods range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using nonviral (polymers, liposomes, and antisense agents) and adenoviral vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. The book offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success.

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