Salivary Gland Cancer: From Diagnosis to Tailored Treatment

Description

This clinically oriented book provides a comprehensive update on the biology, diagnosis, and treatment of salivary gland cancer. Detailed information is presented on molecular characterization and radiological staging, and a series of treatment-related chapters describe the different surgical approaches to major and minor salivary gland cancer, including reconstructive surgery techniques, and the roles of radiotherapy and heavy ion therapy. Rehabilitation, follow-up, and the management of metastatic disease are also fully discussed. The aim is to equip the reader with the knowledge required to deliver appropriate tailored treatment in each patient, based on tumor characteristics and other pertinent factors. An additional feature is the inclusion of information on advocacy groups and their perspectives. All of the chapters are written by leading specialists in the field. In presenting the most recent advances and innovations in diagnosis and therapy and relating them to individualized treatment, this book will appeal to a wide audience including otorhinolaryngologists, head and neck surgeons, maxillofacial surgeons, radiation oncologists, and other clinicians. Front Matter ....Pages i-vi Management-Based Pathology Assessment of Salivary Gland Carcinomas (Adel K. El-Naggar)....Pages 1-16 Molecular Characterization of Salivary Gland Carcinomas (André Fehr, Jörn Bullerdiek, Thorsten Jaekel, Thomas Löning)....Pages 17-32 The Role of Imaging in Staging and Follow-Up of Salivary Gland Tumors (Silvana Sdao, Enrico Civelli, Alessandra Alessi, Giuseppina Calareso)....Pages 33-44 Surgery for Malignant Parotid Gland Tumours (Vincent Vander Poorten)....Pages 45-67 Surgery for Parapharyngeal Tumors (Orlando Guntinas-Lichius)....Pages 69-83 Surgery for Submandibular and Sublingual Malignant Tumors (Natalie L. Silver, Randal S. Weber)....Pages 85-95 Surgery for Malignant Tumors of the Minor Salivary Glands (Davide Lombardi, Remo Accorona, Davide Lancini, Vittorio Rampinelli, Anna Bozzola, Piero Nicolai)....Pages 97-122 Surgical Management of Recurrent Disease (M. Guzzo)....Pages 123-125 Principles of Reconstruction: Reconstruction of the Parotid Area (Silvano Ferrari, Andrea Ferri, Bernardo Bianchi, Enrico Sesenna)....Pages 127-140 Principles of Reconstruction: Palatomaxillary Reconstruction (Cesare Piazza, Alberto Paderno, Piero Nicolai)....Pages 141-157 Salivary Gland Tumors: Radiotherapy (Ester Orlandi, Giuseppe Sanguineti, Carlo Fallai)....Pages 159-193 Protons and Heavy Ions (A. D. Jensen, P. Fossati)....Pages 195-211 Systemic Therapy in Salivary Gland Carcinoma (Laura D. Locati, S. Alfieri, Lisa Licitra)....Pages 213-224