ENGLISH

Multidimensional Liquid Chromatography: Theory and Applications in Industrial Chemistry and the Life Sciences

Book information

Year
2008
ISBN
9780471738473, 9780470276266
DOI
10.1002/9780470276266
Language
english
Format
PDF
Filesize
39 MB (41101576 bytes)
Pages
471\471
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00

Description

Multidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this reference includes chapters contributed by leading experts or teams of experts.Content: Chapter 1 Introduction (pages 1–7): Mark R. Schure and Steven A. CohenChapter 2 Elements of the Theory of Multidimensional Liquid Chromatography (pages 9–34): Mark R. SchureChapter 3 Peak Capacity in Two?Dimensional Liquid Chromatography (pages 35–58): Joe M. DavisChapter 4 Decoding Complex 2D Separations (pages 59–90): Francesco Dondi, Maria C. Pietrogrande, Nicola Marchetti and Attila FelingerChapter 5 Instrumentation for Comprehensive Multidimensional Liquid Chromatography (pages 91–125): Robert E. Murphy and Mark R. SchureChapter 6 Method Development in Comprehensive Multidimensional Liquid Chromatography (pages 127–145): Robert E. Murphy and Mark R. SchureChapter 7 Monolithic Columns and Their 2D?HPLC Applications (pages 147–176): Tohru Ikegami, Hiroshi Aoki, Hiroshi Kimura, Ken Hosoya and Nobuo TanakaChapter 8 Ultrahigh Pressure Multidimensional Liquid Chromatography (pages 177–204): Charles R. Evans and James W. JorgensonChapter 9 Peptidomics (pages 205–219): Egidijus Machtejevas and Klaus K. UngerChapter 10 A Two?Dimensional Liquid Mass Mapping Technique for Biomarker Discovery (pages 221–241): David M. Lubman, Nathan S. Buchanan, Paweena Kreunin, Yanfei Wang, Fred R. Miller, Kathleen Cho, Rong Wu, Steven Goodison and Timothy J. BarderChapter 11 Coupled Multidimensional Chromatography and Tandem Mass Spectrometry Systems for Complex Peptide Mixture Analysis (pages 243–259): Michael P. WashburnChapter 12 Development of Orthogonal 2DLC Methods for Separation of Peptides (pages 261–289): Martin Gilar, Petra Olivova, Amy E. Daly and John C. GeblerChapter 13 Multidimensional Separation of Proteins with Online Electrospray Time?of?Flight Mass Spectrometric Detection (pages 291–317): Steven A. Cohen and Scott J. BergerChapter 14 Analysis of Enantiomeric Compounds Using Multidimensional Liquid Chromatography (pages 319–344): Renee J. Soukup and Daniel W. ArmstrongChapter 15 Two?Dimensional Capillary Electrophoresis for the Comprehensive Analysis of Complex Protein Mixtures (pages 345–363): James R. Kraly, Melissa M. Harwood, Megan Jones and Norman J. DovichiChapter 16 Two?Dimensional HPLC–CE Methods for Protein/Peptide Separation (pages 365–383): Haleem J. Issaq and Timothy D. VeenstraChapter 17 Multidimensional Liquid Chromatography in Industrial Applications (pages 385–423): Frank Rittig and Harald PaschChapter 18 The Analysis of Surfactants by Multidimensional Liquid Chromatography (pages 425–446): Robert E. Murphy and Mark R. Schure

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