ENGLISH

Athymic Nude Rat Brain Atlas

By Anders Björklund , Bengt Mattsson , Malin Parmar

Book information

Publisher
Academic Press
ISBN
9780323997409, 0323997406
Language
english
Format
PDF
Filesize
82 MB (85685973 bytes)
Pages
146\147
Library
SoftArchive
Time added
2023-06-15 20:26:45

Description

Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies. Contains coronal, sagittal, and horizontal maps of young adult athymic nude rat brain, spaced with a distance of 0.2 or 0.25 mmUses "flat skull" Bregma and Lambda as anatomical landmarks for correct placement in the 3D environmentAnatomical structures and nomenclature follow the standard set by the Paxinos and Watson rat brain atlasesIncludes a map of the dopamine projection system as well as the distribution of the A8-A14 dopamine cell groupsAllows for easy read-out of coordinates for precise injections using stereotactic surgery Front Cover Athymic Nude Rat Brain Atlas Copyright Page Table of Contents Introduction Animals Generation of the maps Validation of the stereotactic coordinates Nomenclature Labeling and colors References List of structures Index of Abbreviations Structures organized in regions Coronal sections Sagittal sections Horizontal sections

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