Pulmonary Manifestations of Primary Immunodeficiency Diseases

Description

This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice. Front Matter ....Pages i-ix General Considerations (Mikko Seppänen, Nima Rezaei)....Pages 1-36 Pulmonary Manifestations of Combined T- and B-Cell Immunodeficiencies (Andrew R. Gennery)....Pages 37-75 Pulmonary Manifestations of Predominantly Antibody Deficiencies (Amene Saghazadeh, Nima Rezaei)....Pages 77-120 Pulmonary Manifestations of Congenital Defects of Phagocytes (Seyed Amir Mohajerani, Marzieh Tavakol, Seyed Alireza Mahdaviani)....Pages 121-143 Pulmonary Manifestations of Genetic Disorders of Immune Regulation (Sebastian F. N. Bode, Ulrich Baumann, Carsten Speckmann)....Pages 145-168 Pulmonary Manifestations of Defects in Innate Immunity (Persio Roxo-Junior, Isabela Mina, Catherine Sonaly Ferreira Martins)....Pages 169-192 Pulmonary Manifestations of Autoinflammatory Disorders (Ahmadreza Jamshidi, Saeed Aslani, Mahdi Mahmoudi)....Pages 193-211 Pulmonary Manifestations of Complement Deficiencies (Anete Sevciovic Grumach, Kathleen E. Sullivan)....Pages 213-235 Pulmonary Manifestations of Other Well-Defined Immunodeficiencies (Man Amanat, Mona Salehi, Nima Rezaei)....Pages 237-256 Treatment of Pulmonary Manifestations of Primary Immunodeficiency Diseases (Nahal Mansouri, Davood Mansouri)....Pages 257-267