Physeo Microbiology

Description

MEDICAL COURSE AND STEP 1 REVIEW FIRST EDITION Accompanies online videos taught by Rhett Thomson & Michael Christensen. physeo.com MICROBIOLOGY FUNDAMENTALS Section 1 - Bacterial Structures Section 2 - Virulence Section 3 - Bacterial Genetics Section 4 - Prion Diseases Section 5 - Introduction to Fungi Section 6 - Viral Structures Section 7 - Viral Genetics Section 8 - Viral Genomes and Replication BACTERIA Section 1 - Clostridium tetani Section 2 - Clostridium botulinum Section 3 - Clostridium difficile Section 4 - Clostridium perfringens Section 5 - Bacillus anthracis Section 6 - Bacillus cereus Section 7 - Listeria monocytogenes Section 8 - Corynebacterium diphtheriae Section 9 - Viridans streptococci Section 10 - Streptococcus pneumoniae Section 11 - Streptococcus pyogenes Section 12 - Streptococcus agalactiae Section 13 - Streptococcus gallolyticus Section 14 - Enterococci Section 15 - Staphylococcus aureus Section 16 - Staphylococcus epidermidis Section 17 - Staphylococcus saprophyticus Section 18 - Nocardia Section 19 - Actinomyces israelii Section 20 - Neisseria overview Section 21 - Neisseria meningitidis Section 22 - Neisseria gonorrhoeae Section 23 - Moraxella catarrhalis Section 24 - Haemophilus influenzae Section 25 - Bordetella pertussis Section 26 - Pasteurella multocida, Brucella spp., and Francisella tularensis Section 27 - Salmonella spp. Section 28 - Salmonella typhi Section 29 - Shigella Section 30 - E. coli Section 31 - Klebsiella Section 32 - Proteus mirabilis Section 33 - Pseudomonas aeruginosa Section 34 - Yersinia pestis and enterocolitica Section 35 - Enterobacter, Citrobacter, & Serratia marcescens Section 36 - Bartonella henselae Section 37 - Legionella pneumophila Section 38 - Campylobacter jejuni Section 39 - Vibrio cholerae & Vibrio vulnificus Section 40 - Helicobacter pylori Section 41 - Mycobacterium tuberculosis Section 42 - Mycobacterium leprae Section 43 - Mycobacterium avium-intracellulare, Scrofulaceum, and Marinum Section 44 - Borrelia burgdorferi Section 45 - Leptospira interrogans Section 46 - Treponema pallidum Section 47 - Chlamydia trachomatis, Chlamydophila pneumoniae, and Chlamydophila psittaci Section 48 - Coxiella burnetii Section 49 - Gardnerella vaginalis Section 50 - Mycoplasma pneumoniae Section 51 - Rickettsia prowazekii, Rickettsia rickettsii, and Rickettsia typhi Section 52 - Ehrlichia & Anaplasma Section 53 - Miscellaneous Organisms FUNGI Section 1 - Histoplasma capsulatum Section 2 - Blastomyces dermatitidis Section 3 - Coccidioides immitis Section 4 - Paracoccidioides brasiliensis Section 5 - Microsporum, Trichophyton, and Epidermophyton Section 6 - Malassezia furfur Section 7 - Sporothrix schenckii Section 8 - Candida albicans Section 9 - Aspergillus fumigatus Section 10 - Cryptococcus neoformans Section 11 - Mucor & Rhizopus spp. Section 12 - Pneumocystis jirovecii PARASITES Section 1 - Giardia lamblia Section 2 - Entamoeba histolytica Section 3 - Cryptosporidium Section 4 - Toxoplasma gondii Section 5 - Naegleria fowleri Section 6 - Trypanosoma brucei, gambiense, and rhodesiense Section 7 - Malaria Section 8 - Babesia Section 9 - Trypanosoma cruzi Section 10 - Leishmania donovani Section 11 - Trichomonas vaginalis Section 12 - Enterobius vermicularis (pinworm) Section 13 - Ascaris lumbricoides (giant roundworm) Section 14 - Strongyloides stercoralis (threadworm) Section 15 - Ancylostoma duodenale and Necator americanus (hookworms) Section 16 - Trichinella spiralis Section 17 - Trichuris trichiura (whipworm) Section 18 - Toxocara canis Section 19 - Onchocerca volvulus Section 20 - Loa loa and Wuchereria bancrofti Section 21 - Taenia solium Section 22 - Diphyllobothrium latum Section 23 - Echinococcus granulosus Section 24 - Schistosoma haematobium, mansoni, and japanicom Section 25 - Clonorchis sinensis Section 26 - Sarcoptes scabiei Section 27 - Pediculus corporis, pubis and capitis VIRUSES Section 1 - Herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2) Section 2 - Varicella-zoster virus (VZV) Section 3 - Epstein-Barr Virus (EBV) Section 4 - Cytomegalovirus (CMV) Section 5 - Roseola (HHV-6 and HHV-7) Section 6 - Kaposi sarcoma (HHV-8) Section 7 - Hepatitis B Virus (HBV) Section 8 - Smallpox, Cowpox, and Molluscum contagiosum Section 9 - Human papillomavirus Section 10 - Adenovirus Section 11 - JC Virus and BK Virus Section 12 - Parvovirus B19 Section 13 - Coronavirus and SARS Section 14 - Human immunodeficiency virus (HIV) Section 15 - Human T-lymphotropic virus (HTLV) Section 16 - Hepatitis C Virus (HCV) Section 17 - Yellow fever Section 18 - Dengue Fever Section 19 - West Nile Virus and St. Louis Encephalitis Section 20 - Zika Virus Section 21 - Rubella Section 22 - Eastern, Western, and Venezuelan equine encephalitis viruses; Chikungunya virus Section 23 - California Encephalitis Section 24 - Rift Valley Fever and Crimean-Congo Hemorrhagic Fever Virus Section 25 - Hantavirus Section 26 - Influenza virus Section 27 - Lassa fever encephalitis and Lymphocytic choriomeningitis virus Section 28 - Hepatitis D Virus Section 29 - Parainfluenza Virus Section 30 - RSV and hMPV Section 31 - Measles Section 32 - Mumps Section 33 - Rabies Virus Section 34 - Ebola Virus and Marburg Virus Section 35 - Norovirus Section 36 - Hepatitis E virus Section 37 - Rotavirus and Colorado Tick Fever Section 38 - Poliovirus Section 39 - Echovirus Section 40 - Rhinovirus Section 41 - Coxsackieviruses (A & B) Section 42 - Hepatitis A Virus Table 5.1.1 - Bacterial structures Figure 5.1.1 - Gram positive bacterial envelope Figure 5.1.2 - Gram negative bacterial envelope Figure 5.1.3 - Envelope of Mycoplasma spp. Figure 5.1.4 - Envelope of Mycobacteria spp. Figure 5.1.5 - Acid-fast stain of Mycobacterium Tuberculosis Figure 5.1.6 - Bacterial endospore Table 5.1.2 - Overview of virulence factors Figure 5.1.7 - Protein A mechanism Figure 5.1.8 - Visual demonstration of Type III secretion systems Table 5.1.3 - Bacterial exotoxins Figure 5.1.9 - Exotoxins that inhibit protein synthesis Figure 5.1.10 - Exotoxins that increase fluid secretion using adenylate cyclase Figure 5.1.11 - Exotoxin (heat-stable toxin) that increases fluid secretion through guanylate cyclase Figure 5.1.12 - Pertussis toxin mechanism Figure 5.1.13 - Mechanism of tetanospasmin Figure 5.1.14 - Mechanism of botulinum toxin Figure 5.1.15 - Mechanism of exotoxins that disrupt cell membranes Figure 5.1.16 - Mechanism of superantigens Table 5.1.4 - Mechanisms of genetic change in bacteria Figure 5.1.17 - Random mutation in bacteria Figure 5.1.18 - Phase variation in bacteria Figure 5.1.19 - Transformation in bacteria Figure 5.1.20 - Conjugation in bacteria Figure 5.1.21 - Generalized transduction (lytic cycle) Figure 5.1.22 - Specialized transduction (lysogenic cycle) Figure 5.1.23 - Restriction modification Figure 5.1.24 - Brain biopsy with vacuolations from spongiform encephalopathy Figure 5.1.25 - Fungi structure Figure 5.1.26 - Filamentous fungus Figure 5.1.27 - Mold (left) and yeast (right) Figure 5.1.28 - Spores of Aspergillus Figure 5.1.29 - Enveloped virus structures Figure 5.1.30 - Naked virus structures Figure 5.1.31 - Adsorption, penetration, and uncoating of naked viruses Figure 5.1.32 - Adsorption, penetration, and uncoating of enveloped viruses Figure 5.1.33 - Bacteriophage structure Table 5.1.5 - Genetic adjustments and activities in viruses Figure 5.1.34 - Genetic shift and genetic drift Figure 5.1.35 - Phenotypic mixing Figure 5.1.36 - HDV superinfection Figure 5.1.37 - Positive-sense and negative-sense viruses Figure 5.1.38 - Poxvirus cytoplasm replication Figure 5.1.39 - HBV structure Figure 5.1.40 - RNA virus replication Figure 5.1.41 - DNA virus replication Figure 5.2.1 - Bacteria overview figure Figure 5.2.2 - Gram stain Figure 5.2.3 - Gram-positive bacilli Figure 5.2.4 - Tetanospasmin Figure 5.2.5 - Gram stain of Clostridium botulinum Figure 5.2.6 - Gram stain of Clostridium difficile Figure 5.2.7 - Pseudomembranous colitis Figure 5.2.8 - Gram stain of Clostridium perfringens Figure 5.2.9 - Gas gangrene Figure 5.2.10 - Gram stain of Bacillus anthracis Figure 5.2.11 - Cutaneous anthrax Figure 5.2.12 - Gram stain of Bacillus cereus Figure 5.2.13 - Gram stain of gram-positive rods Figure 5.2.14 - Hemolysis on 5% sheep blood agar Figure 5.2.15 - Catalase test Figure 5.2.16 - Gram stain of Corynebacterium diphtheriae Figure 5.2.17 - Cystine-tellurite agar Figure 5.2.18 - Pseudomembranous pharyngitis Figure 5.2.19 - Gram stain of Streptococci Figure 5.2.20 - Microbial resistance and sensitivity to various compounds Figure 5.2.21 - Splinter hemorrhages Figure 5.2.22 - Quellung reaction Figure 5.2.23 - Otitis media Figure 5.2.24 - Cellulitis Figure 5.2.25 - Impetigo Figure 5.2.26 - Erysipelas Figure 5.2.27 - Sandpaper-like rash Figure 5.2.28 - Strawberry tongue Figure 5.2.29 - GAS pharyngitis Figure 5.2.30 - CAMP test Figure 5.2.31 - Gram stain of Enterococci Figure 5.2.32 - Gram stain of Staphylococcus Figure 5.2.33 - Mannitol fermentation test Figure 5.2.34 - Coagulase test tube Figure 5.2.35 - Urease test Figure 5.2.36 - Gram stain of Nocardia Figure 5.2.37 - Acid-fast stain of Mycobacterium Tuberculosis (similar to Nocardia) Figure 5.2.38 - Gram stain of Actinomyces Figure 5.2.39 - Sulfur granule Figure 5.2.40 - Gram stain of Neisseria Figure 5.2.41 - Chocolate agar Figure 5.2.42 - Gram negative bacterial cell wall Figure 5.2.43 - Oxidase test Figure 5.2.44 - Chocolate agar and Thayer-Martin agar Figure 5.2.45 - Gram stain of Moraxella Figure 5.2.46 - Otoscopic view of otitis media Figure 5.2.47 - Gram Stain of Haemophilus influenzae Figure 5.2.48 - Satellite colonies of Haemophilus influenzae growing near Staphylococcus aureus on blood agar Figure 5.2.49 - Epiglottis Figure 5.2.50 - Thumb sign Figure 5.2.51 - Cherry red epiglottis Figure 5.2.52 - Gram stain of Bordetella Figure 5.2.53 - Regan-Lowe agar Figure 5.2.54 - Gram stain of gram-negative coccobacilli Figure 5.2.55 - Granuloma Figure 5.2.56 - Gram stain of Salmonella Figure 5.2.57 - TSI agar Figure 5.2.58 - Peyer’s patches Figure 5.2.59 - Rose spots Figure 5.2.60 - Gram stain of Shigella Figure 5.2.61 - Actin Figure 5.2.62 - Neutrophils Figure 5.2.63 - Schistocytes Figure 5.2.64 - Gram stain of E. coli Figure 5.2.65 - Eosin methylene blue aga Figure 5.2.66 - MacConkey agar Figure 5.2.67 - Indole test Figure 5.2.68 - Lipopolysaccharide Figure 5.2.69 - Mucoid colonies Figure 5.2.70 - Struvite crystals Figure 5.2.71 - Staghorn calculus Figure 5.2.72 - Gram stain of Pseudomonas Figure 5.2.73 - Pyoverdin and pyocyanin (bluish-green color) of Pseudomonas (left) Figure 5.2.74 - Corneal abrasion Figure 5.2.75 - Otitis externa Figure 5.2.76 - Hot tub folliculitis Figure 5.2.77 - Gram stain gram of Yersinia enterocolitica Figure 5.2.78 - Axillary Bubo Figure 5.2.79 - Gram stain of Enterobacter Figure 5.2.80 - Red pigment from Serratia on a piece of bread Figure 5.2.81 - Warthin-Starry stain Figure 5.2.82 - Gram stain of Legionella Figure 5.2.83 - Silver stain of Legionella Figure 5.2.84 - Buffered charcoal yeast extract agar Figure 5.2.85 - Gram stain Campylobacter Figure 5.2.86 - Gram stain of Vibrio cholerae Figure 5.2.87 - “Rice-water” diarrhea Figure 5.2.88 - Hematoxylin and eosin (H&E) stain of the gastric mucosa Figure 5.2.89 - Silver based stain Figure 5.2.90 - Stomach anatomy and physiology Figure 5.2.91 - Acid-fast stain of Mycobacterium tuberculosis Figure 5.2.92 - Lowenstein-Jensen medium Figure 5.2.93 - Pathophysiology of Mycobacterium tuberculosis Figure 5.2.94 - Miliary tuberculosis Figure 5.2.95 - “Serpentine cords” Figure 5.2.96 - PPD test Figure 5.2.97 - Ghon complex Figure 5.2.98 - Acid-fast stain of Mycobacterium leprae Figure 5.2.99 - Pathophysiology of Mycobacterium leprae Figure 5.2.100 - Leonine Facies Figure 5.2.101 - Acid-fast stain of Mycobacterium avium-intracellulare Figure 5.2.102 - Spirochetes via dark-field microscopy Figure 5.2.103 -  Ixodes deer tick Figure 5.2.104 - Giemsa stain of Borrelia Figure 5.2.105 - Erythema migrans Figure 5.2.106 - Bell’s palsy Figure 5.2.107 - Electron microscopic image of Leptospira interrogans Figure 5.2.108 - Dark-field photomicrograph of Treponema pallidum Figure 5.2.109 - Chancre Figure 5.2.110 - Maculopapular rash Figure 5.2.111 - Maculopapular rash on the palms Figure 5.2.112 - Condyloma lata Figure 5.2.113 - Gumma Figure 5.2.114 - Cross section of the spinal cord Figure 5.2.115 - Notched teeth Figure 5.2.116 - Saddle nose Figure 5.2.117 - Rhagades Figure 5.2.118 - Life cycle of Chlamydia trachomatis Figure 5.2.119 - Giemsa stain of Chlamydia Figure 5.2.120 -  Gram stain of Coxiella burnetii Figure 5.2.121 -  Osler’s nodes Figure 5.2.122 - Clue cells Figure 5.2.123 - IgM antibodies Figure 5.2.124 - Rocky Mountain Spotted Fever Figure 5.2.125 - Weil Felix Test Figure 5.2.126 - Ehrlichia within a monocyte Figure 5.2.127 - Anaplasma within a granulocyte Table 5.2.1 - Miscellaneous organisms Figure 5.2.128 - Intestinal biopsy in Whipple disease Figure 5.2.129 - Granuloma inguinale caused by Klebsiella granulomatis (male) Figure 5.2.130 - Granuloma inguinale caused by Klebsiella granulomatis (female) Figure 5.2.131 - Bipolar Donovan bodies from granuloma inguinale ulcer biopsy Figure 5.3.1 - Fungi overview figure Figure 5.3.2 - Histoplasma capsulatum yeast in macrophages Figure 5.3.3 - Mold (left) and yeast (right) Figure 5.3.4 - Verrucous skin lesion Figure 5.3.5 - Squamous cell carcinoma Figure 5.3.6 - Granulomatous nodule Figure 5.3.7 - Broad-based budding by Blastomyces dermatitidis Figure 5.3.8 - Endospore of Coccidioides immitis Figure 5.3.9 - Coccidioides using the methenamine silver stain Figure 5.3.10 - Erythema multiforme Figure 5.3.11 - Erythema nodosum Figure 5.3.12 - Budding cells of Paracoccidioides brasiliensis Figure 5.3.13 - Hyphae and spores of a dermatophyte Figure 5.3.14 - Tinea capitis Figure 5.3.15 - Tinea corporis Figure 5.3.16 - Tinea pedis Figure 5.3.17 - Vesicular athlete’s foot Figure 5.3.18 - Interdigital tinea pedis Figure 5.3.19 - Onychomycosis Figure 5.3.20 - Tinea cruris Figure 5.3.21 - Tinea versicolor skin lesions Figure 5.3.22 - Microscopic image of Malassezia furfur “Spaghetti and meatballs” Figure 5.3.23 - Sporothrix schenckii (yeast form) Figure 5.3.24 - Sporothrix schenckii (mold form) Figure 5.3.25 - Sporothrix schenckii lesion along draining lymphatic channels Figure 5.3.26 - Pseudohyphae and budding yeast Figure 5.3.27 - Germ tube formation Figure 5.3.28 - Oral thrush Figure 5.3.29 - Esophageal candidiasis Figure 5.3.30 - Vulvovaginitis caused by Candida albicans Figure 5.3.31 - Microscopic morphology of Aspergillus fumigatus Figure 5.3.32 - Aspergilloma (gross image) Figure 5.3.33 - Aspergilloma (imaging) Figure 5.3.34 - India ink stain Figure 5.3.35 - Sabouraud dextrose agar Figure 5.3.36 - Mucicarmine stain Figure 5.3.37 - Microscopy of mucormycosis Figure 5.3.38 - Silver stain of Pneumocystis jirovecii cysts Figure 5.3.39 - Chest x-rays of Pneumocystis pneumonia with “ground glass” opacities Figure 5.3.40 - Pneumatoceles Figure 5.3.41 - Fluorescent antibody stain Figure 5.4.1 - Parasites overview figure Figure 5.4.2 - Giardia lamblia cyst Figure 5.4.3 - Giardia lamblia trophozoite Figure 5.4.4 - Red blood cells within Entamoeba cytoplasm (erythrophagocytosis) Figure 5.4.5 - Entamoeba egg in stool sample Figure 5.4.6 - Cryptosporidium oocysts with acid-fast staining Figure 5.4.7 - Trypomastigotes on peripheral blood smear Figure 5.4.8 - Malaria Life Cycle Figure 5.4.9 - Plasmodium trophozoite ring form within red blood cells Figure 5.4.10 - Babesia trophozoite ring form (“Maltese cross”) within red blood cells Figure 5.4.11 - Barium esophagram showing achalasia Figure 5.4.12 - Cutaneous leishmaniasis Figure 5.4.13 - Flagellated Gardnerella trophozoites Figure 5.4.14 - Gardnerella vaginalis on saline microscopy Figure 5.4.15 - Pinworm egg Figure 5.4.16 - Life cycle of parasites that cause Löffler syndrome Figure 5.4.17 - Ascaris lumbricoides egg Figure 5.4.18 - Strongyloides stercoralis larva Figure 5.4.19 - Hookworm egg Figure 5.4.20 - Cutaneous hookworm lesion Figure 5.4.21 - Striated muscle tissue infected with Trichinella spiralis Figure 5.4.22 - Periorbital edema Figure 5.4.23 - Whipworm egg Figure 5.4.24 - Blackfly Figure 5.4.25 - Elephantiasis Figure 5.4.26 - Taenia solium life cycle Figure 5.4.27 - Taenia solium on microscopy Figure 5.4.28 - Taenia solium egg in stool sample Figure 5.4.29 - Neurocysticercosis on imaging Figure 5.4.30 - Echinococcus granulosus life cycle Figure 5.4.31 - Echinococcus granulosus tapeworm on microscopy Figure 5.4.32 - Liver hydatid cyst on MRI Figure 5.4.33 - Liver hydatid cyst (gross) Figure 5.4.34 - Schistosoma life cycle Figure 5.4.35 - Lateral spine on Schistosoma egg (mansoni or japanicom) Figure 5.4.36 - Lateral spine on Schistosoma haematobium egg Figure 5.4.37 - Scabies-related erythematous papules Figure 5.4.38 - Pediculus capitis louse Figure 5.4.39 - Pediculus nit on hair shaft Figure 5.4.40 - Pediculus pubis louse Figure 5.4.41 - Pediculus corporis louse Figure 5.4.42 - Virus overview figure Figure 5.4.43 - Trigeminal ganglion Figure 5.4.44 - Gingivostomatitis Figure 5.4.45 - Viral keratoconjunctivitis Figure 5.4.46 - Herpetic whitlow Figure 5.4.47 - Herpes labialis Figure 5.4.48 - Erythema multiforme Figure 5.4.49 - HSV-related esophageal ulcers Figure 5.4.50 - MRI of temporal lobe encephalitis Figure 5.4.51 - Neonatal herpes Figure 5.4.52 - Vesicular and ulcerative herpes lesions Figure 5.4.53 - Multinucleated giant cells on Tzanck smear Figure 5.4.54 - Cowdry bodies in hepatocytes Figure 5.4.55 - Chickenpox Figure 5.4.56 - Shingles Figure 5.4.57 - Herpes zoster ophthalmicus Figure 5.4.58 - Cytotoxic T-cells on EBV-related peripheral blood smear Figure 5.4.59 - Starry sky appearance on biopsy of Burkitt’s lymphoma Figure 5.4.60 - MRI showing ring-enhancing lesion Figure 5.4.61 - CMV retinitis Figure 5.4.62 - “Blueberry muffin” rash Figure 5.4.63 - Periventricular calcifications on CT imaging Figure 5.4.64 - Owl’s eye appearance on lung biopsy Figure 5.4.65 - Skin lesions in Kaposi’s sarcoma Figure 5.4.66 - HBV structure Table 5.4.1 - Descriptions of serologic markers in Hepatitis B Figure 5.4.67 - Serological markers in acute hepatitis B infection Figure 5.4.68 - Serological markers in chronic hepatitis B infection Figure 5.4.69 - H&E stain showing ground glass appearance Figure 5.4.70 - Reverse transcriptase in HBV Figure 5.4.71 - Smallpox Figure 5.4.72 - Umbilicated lesions in Molluscum contagiosum Figure 5.4.73 - Plantar warts Figure 5.4.74 - Anal warts Figure 5.4.75 - HPV carcinogenesis mechanism Figure 5.4.75 - Koilocytes on Pap smear Figure 5.4.77 - Progressive multifocal leukoencephalopathy (PML) on MRI Figure 5.4.78 - Fifth disease Figure 5.4.79 - HIV structure Figure 5.4.80 - HIV replication cycle Figure 5.4.81 - Time course of HIV infection Figure 5.4.82 - HIV diagnosis Figure 5.4.83 - Fat and lymphoid aggregates seen on HCV liver biopsy Figure 5.4.84 - Lichen planus Figure 5.4.85 - Maculopapular rash of Rubella Figure 5.4.86 - Chikungunya-related erythematous maculopapular rash Figure 5.4.87 - Genetic shift and genetic drift Figure 5.4.88 - Acute HDV-HBV coinfection Figure 5.4.89 - HDV superinfection Figure 5.4.90 - Steeple sign on radiograph in croup Figure 5.4.91 - Bronchiolitis on chest radiograph Figure 5.4.92 - Maculopapular rash in measles Figure 5.4.93 - Koplik’s spots Figure 5.4.94 - Giant cells Figure 5.4.95 - Mumps-related parotitis Figure 5.4.96 - Rabies virus structure Figure 5.4.97 - Rabies virus bullet-shaped envelopes on electron microscopy Figure 5.4.98 - Rabies virus Negri bodies Figure 5.4.99 - Retrograde movement of Rabies virus Figure 5.4.100 - Positive-sense and negative-sense viruses Figure 5.4.101 - Transmission electron micrograph of Rotavirus Figure 5.4.102 - Coxsackie-related palmar vesicular lesions Figure 5.4.103 - Coxsackie-related plantar vesicular lesions Figure 5.4.104 - Coxsackie-related oropharyngeal vesicular lesions (herpangina) Figure 5.4.105 - Councilman bodies in HAV