The Regeneration Promise: The Facts behind Stem Cell Therapies

Description

The Regeneration Promise is a reader-friendly guide to the world of regenerative medicine and stem cell technology. It covers the history of stem cell technology as a general introduction to the subject and then continues with a description of the many known types of stem cells and how these can potentially be used to treat disease. The author explains the pros and cons of using stem cell technology to treat patients in simple and factual terms throughout the book while clarifying many stem cell myths. There is valuable advice for people considering undergoing stem cell therapy and also for those who are considering stem cell storage such as umbilical cord blood storage at the birth of a baby. The book also covers information on current research in stem cell technology and how this may be useful in the clinic, as promising regenerative medicine treatments emerge in the near future. The simple use of language with a clear explanation of scientific terms, where applicable, makes this book an accessible source of information for anyone interested in enhancing their general knowledge about regenerative medicine when considering such treatment options and understanding the debate surrounding stem cell technology and its use in disease therapy. Cover Title Copyright End User License Agreement Contents Preface CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS Dedication A Bit of History Peter Hollands INTERESTING TIMES STEM CELLS ARE EVERYWHERE! Bone Marrow Stem Cells Back Again to 1956 Tissue Typing or ‘Tissue Matching’ From Embryos to Stem Cells From Mouse to Man? More Mouse Embryos! Stem Cells in The Blood Cord Blood Stem Cells Cord Blood Transfusion Human Embryonic Stem Cells Adult or Fetal Stem Cells? Umbilical Cord Tissue and Placental Tissue Stem Cells Fat Stem Cells! The Tooth Fairy and Stem Cells ‘Man Made’ Stem Cells INITIAL CONCLUSIONS KEY POINTS OF CHAPTER 1 Blood and Toil Peter Hollands ‘BLOOD FORMING’ STEM CELLS Bone Marrow Transplantation Haploidentical Transplantation Find the Match Bone Marrow Stem Cell Banks Preparation for Transplant Transplant Time Recovery It’s Not Easy! ‘TISSUE FORMING’ STEM CELLS IN BONE MARROW Clinical Trials Four Phases BONE MARROW STEM CELLS AND HEART ATTACK BONE MARROW STEM CELLS AND AUTOIMMUNE DISEASE THE RIGHT STEM CELL AND A HOLISTIC APPROACH BONE MARROW STEM CELLS AND OSTEOARTHRITIS Clinical Trials BONE MARROW AND OTHER DISEASES KEY POINTS OF CHAPTER 2 A Bouncing Baby! Peter Hollands CORD BLOOD STEM CELLS Cord Blood Stem Cell Collection Process Cord Blood Stem Cell Storage Options Cord Blood Laboratory Processing Cord Blood Stem Cells Pros and Cons Cord Blood Stem Cell Double Transplants and Expansion Quality not Quantity Cord Blood Stem Cell Clinical Trial for Cerebral Palsy Cord Blood Stem Cell Clinical Trial for Autism KEY POINTS OF CHAPTER 3 Baby Blues Peter Hollands CHOICES Public and Private Cord Blood Banks The Development of Private Cord Blood Banking The Development of Public Cord Blood Banking Public or Private Cord Blood Storage? Cord Blood Guidance Whole or Processed? More Questions To Clamp or Not to Clamp? That is the Question… The UK Royal Colleges Umbilical Cord Blood Plasma KEY POINTS OF CHAPTER 4 That's a Nice Vein Peter Hollands PERIPHERAL BLOOD STEM CELLS Potential Problems Improved Mobilisation Technology Clinical Trials Using Peripheral Blood Stem Cells KEY POINTS OF CHAPTER 5 The Vatican and More Peter Hollands A COMPLEX DEBATE Human Embryonic Stem Cell Production The Human Embryo Is There an Elephant in The Room? Clinical Trials A FINAL NOTE OF OPTIMISM! KEY POINTS OF CHAPTER 6 No One Likes the Dentist Peter Hollands OFF TO SEE THE DENTIST Milk and Adult Teeth Milk Teeth Collection Stem Cells from Adult Teeth Are There Enough Stem Cells? Tooth Implants Clinical Trial KEY POINTS OF CHAPTER 7 Who Are You Calling Fat? Peter Hollands FAT: GOOD OR BAD? Liposuction Processing of Fat Stem Cells Using Enzymes Processing of Fat Stem Cells Using A Mechanical Approach Caution is Needed Clinical Trials and ‘Freeze Young’ Fat Stem Cells and Osteoarthritis KEY POINTS OF CHAPTER 8 A Human Touch Peter Hollands MAN-MADE Good or Bad? Organoids Clinical Trials KEY POINTS OF CHAPTER 9 Baby is Back! Peter Hollands STEM CELLS IN TISSUES RELATED TO PREGNANCY Umbilical Cord Tissue Clinical Trials of Cord Tissue Stem Cells Placenta Stem Cells Amniotic Membrane and Amniotic Fluid Stem Cells Clinical Trials of Amniotic Membrane Stem Cells Research and Clinical Trial of Amniotic Membrane Stem Cells KEY POINTS OF CHAPTER 10 Kill or Cure? Peter Hollands STEM CELL TREATMENTS (CAVEAT EMPTOR: BUYER BEWARE) The Regeneration Promise Human Use Using Your Own Stem Cells Celebrity Endorsement There is Hope KEY POINTS OF CHAPTER 11 A Final Thought Peter Hollands SOME THINGS WORK SOME THINGS DO NOT Cord Blood Transfusion Platelet Rich Plasma (PRP) Very Small Embryonic Like Stem Cells and Laser Technology Cell Reprogramming Exosomes Quantum Medicine Nanotechnology 3D Printing Skeletal Muscle Stem Cells Liver Stem Cells Recent Progress in Stem Cell Therapy of Heart Disease Anti-Ageing A Final Thought KEY POINTS OF CHAPTER 12 SUGGESTED FURTHER READING USEFUL LINKS Glossary GLOSSARY Subject Index Back Cover