Pervasive Cardiovascular and Respiratory Monitoring Devices: Model-Based Design
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Pervasive Cardiac and Respiratory Monitoring Devices: Model-Based Design is the first book to combine biomedical instrumentation and model-based design. As the scope is limited to cardiac and respiratory devices only, this book offers more depth of information on these devices; focusing in on signals used for home monitoring and offering additional analysis of these devices. The author offers an insight into new industry and research trends, including advances in contactless monitoring of breathing and heart rate. Each chapter presents a section on current trends. As instrumentation as a field is becoming increasingly smart, basic signal processing is also discussed. Real case-studies for each modelling approach are used, primarily covering blood pressure, ECG and radar-based devices. This title is ideal for teaching and supporting learning as it is written in an accessible style and a solutions manual for the problem sets is provided. It will be useful to 4th year undergraduate students, graduate/masters/PhD students, early career researchers and professionals working on an interdisciplinary project; as it introduces the field and provides real world applications. For engineers this book solves the problem of how to assess and calibrate a medical device to ensure the data collected is trustworthy. For students, this book allows for trying concepts and circuits via simulations and learning modeling techniques. Students will learn concepts from this book and be ready to design bioinstrumentations devices based on specifications/requirements. Focuses on model-based design using Simscape/MATLAB; learn how to design a system and how to evaluate how different choices affect the output of the systemCovers pervasive monitoring: shows how to design optimal solutions for pervasive and personalized healthcare monitoringExplores uncertainty and sensitivity analysis; understand your model better Title page Table of Contents Copyright Dedication Preface Acknowledgments Overview of biomedical instrumentation and devices Abstract Abbreviations and explanations 1. Introduction 2. Pervasive devices 3. Biomedical devices for cardiac and respiratory monitoring 4. Modeling and simulation 5. Design cycle 6. Biomedical device components and design issues 7. Organization of the book 8. Summary 9. Problems 10. Further reading Chapter 1. Concepts in performance evaluation and uncertainty analysis 1.1. Introduction 1.2. Basic probabilistic concepts 1.3. Performance metrics 1.4. Measuring agreement 1.5. Uncertainty in measurements 1.6. Summary 1.7. Problems 1.8. Further reading Chapter 2. Transducers 2.1. Introduction 2.2. Strain gauges 2.3. Piezoelectric transducers 2.4. Capacitive transducers 2.5. Optical sensors 2.6. Electrodes 2.7. Summary 2.8. Appendix 2.9. Problems 2.10. Further reading Chapter 3. Electronics 3.1. Introduction 3.2. Wheatstone bridge 3.3. Amplifiers and their configurations 3.4. Analog filters 3.5. Analog-to-digital converter 3.6. Generating signals 3.7. Other components of the system 3.8. Summary 3.9. Problems 3.10. Further reading Chapter 4. Modeling and simulation of biomedical systems 4.1. Introduction 4.2. Data collection and databases 4.3. Models for signal generation 4.4. Modeling noise and assessing signal quality 4.5. Uncertainty propagation in systems 4.6. Modeling software 4.7. Modeling power consumption 4.8. Summary 4.9. Problems 4.10. Further reading Chapter 5. Devices based on oscillometric signal: blood pressure 5.1. Introduction 5.2. What is measured using a blood pressure device 5.3. Features of the signal and the noise 5.4. Performance measures and evaluation 5.5. Oscillometric signal generation model 5.6. Oscillometric algorithm 5.7. Sensors and circuits 5.8. Simulation of the overall system 5.9. Improving oscillometric methods and devices 5.10. Oscillometry and arterial stiffness 5.11. Summary 5.12. Appendix A 5.13. Problems 5.14. Further reading Chapter 6. Devices based on photoplethysmogram and pulse oximetry 6.1. Introduction 6.2. What is measured using pulse oximeters and PPG devices? 6.3. Signal properties and noise characterization 6.4. Performance measures 6.5. Simulating the propagation of light through the tissue in reflectance-mode pulse oximetry 6.6. Sensors and circuits 6.7. PPG system 6.8. Pulse oximeters 6.9. New developments 6.10. Summary 6.11. Problems 6.12. Further reading Chapter 7. Devices based on the ECG signal 7.1. Introduction 7.2. What is measured using ECG 7.3. Signal properties, simulators, and databases 7.4. Types of devices and standards 7.5. Processing the ECG signal 7.6. Implementation of a single-lead ECG system 7.7. Current trends and research directions 7.8. Heart rate variability 7.9. Summary 7.10. Appendix: segmentation of the ECG signal 7.11. Problems 7.12. Further reading Chapter 8. Devices based on the time difference between signals: continuous blood pressure measurement 8.1. Introduction 8.2. Temporal relationship between signals 8.3. Modeling the relationship between PTT and blood pressure 8.4. Cuffless, continuous blood pressure monitoring 8.5. Other applications of PTT/PAT 8.6. Summary 8.7. Appendix 1—data collection system 8.8. Problems 8.9. Further reading Chapter 9. Continuous monitoring of breathing 9.1. Introduction 9.2. What is measured? 9.3. Features of the signal and the noise 9.4. Breathing rate estimation 9.5. Tidal volume and flow estimation 9.6. Breathing pattern classification 9.7. Conclusion 9.8. Problems 9.9. Further reading Chapter 10. Wearable devices 10.1. Introduction 10.2. Sensors and sensing modality 10.3. Classifications of wearable devices 10.4. Designing for low power 10.5. Examples of wearable devices 10.6. Summary 10.7. Problems 10.8. Further reading Chapter 11. Conclusion and research directions: beyond wearable devices 11.1. Introduction 11.2. What was covered in the book 11.3. Trends and research directions for biomedical devices 11.4. Beyond wearable devices: touch and proximity 11.5. Beyond wearable devices: contactless monitoring 11.6. Combining all: pervasive health monitoring systems 11.7. Conclusion Index
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