Lung Transplantation

Description

This book details all aspects of lung transplantation and equips the general pulmonologist/physician with the necessary tools and knowledge to assist patients with the preparation for and care post lung transplantation. Written by global experts, chapters present general principles and history; indications and eligibility for lung transplantation, including screening for COPD, cystic fibrosis, scleroderma, Idiopathic pulmonary fibrosis (IPF) and idiopathic pulmonary arterial hypertension; approach to and complications of lung transplantation, such as prognostic markers, radiological approach, and immunology and rejection; and medical and surgical guidelines for lung transplantation. The goal of lung transplantation is to increase survival and to provide a greater quality of life for patients with untreatable end-stage lung disease and this book serves to best prepare clinicians in achieving that goal. Lung Transplantation: Evolving knowledge and New horizons offers valuable insights into this modality and is an authoritative resource for multidisciplinary services that include experts in pulmonary diseases, critical care, cardiology, thoracic surgery, infection diseases, internal medicine, radiology , immunology, nephrology, rehabilitation, psychology /psychiatry, nurses, social workers and nutritionists. Front Matter ....Pages i-xviii Front Matter ....Pages 1-1 The History of Lung Transplantation (Andrea Maria D’Armini, Valentina Grazioli, Mario Viganò)....Pages 3-15 Single- and Bilateral Lung Transplantation: Indications, Contraindications, Evaluation, and Requirements for Patients to Be Considered Eligible (Gerard J. Meachery, Paul A. Corris)....Pages 17-40 Pretransplant Considerations in Patients with Obstructive Lung Disease: COPD, Lymphangioleiomyomatosis, Cystic Fibrosis, and Non-CF Bronchiectasis (Shahnaz Ajani, Robert M. Kotloff)....Pages 41-56 Pretransplant Considerations in Patients with Pulmonary Fibrosis (Roberto G. Carbone, Assaf Monselise, Keith M. Wille, Giovanni Bottino, Francesco Puppo)....Pages 57-70 Pulmonary Vascular Disease: Specific Evaluation and Timing for Listing Eligible Patients to Receive Lung Transplantation and Management of the Pre-lung Transplant Patient (Alison S. Witkin, Richard N. Channick)....Pages 71-84 Psychosocial Evaluation of the Patient Considered for Lung Transplant (Thomas M. Soeprono, Ganesh Raghu)....Pages 85-92 Prognostic Markers and the LAS for Lung Transplantation: Impact of New Revisions for Successful Outcome (M. Patricia George, Matthew R. Pipeling)....Pages 93-109 Front Matter ....Pages 111-111 Management of the Donor and Recipient: Surgical Management (Andrea Mariscal, Shaf Keshavjee)....Pages 113-137 Immunology in Lung Transplantation (Idoia Gimferrer, Karen A. Nelson)....Pages 139-160 Physiologic and Epigenetic Changes with Pulmonary Vascular Injury After Lung Transplantation (Steven Kenneth Huang, Roberto G. Carbone, Giovanni Bottino)....Pages 161-182 Front Matter ....Pages 183-183 Medical Management of the Lung Transplant Recipient: Extrapulmonary Issues (Erika D. Lease, Ganesh Raghu)....Pages 185-194 Management of Cellular and Humoral Rejection: Prevention, Diagnosis, and Treatment (Erika D. Lease, Ganesh Raghu)....Pages 195-207 Pathology of Lung Rejection: Cellular and Humoral Mediated (Anja C. Roden, Henry D. Tazelaar)....Pages 209-230 Prevention and Treatment Regimens for Non-viral Infections in the Lung Transplant Recipient (Martin R. Zamora)....Pages 231-240 Respiratory Viruses and Other Relevant Viral Infections in the Lung Transplant Recipient (Ali Abedi, Reed Hall, Deborah Jo Levine)....Pages 241-262 Lung Allograft Dysfunction (LAD) and Bronchiolitis Obliterans Syndrome (Bart Vanaudenaerde, Robin Vos, Stijn Verleden, Elly Vandermeulen, Geert Verleden)....Pages 263-278 Gastroesophageal Reflux and Esophageal Dysmotility in Patients Undergoing Evaluation for Lung Transplantation: Assessment, Evaluation, and Management (Robert B. Yates, Carlos A. Pellegrini, Brant K. Oelschlager)....Pages 279-299 Management of Airway Stenosis in the Lung Allograft: Bronchoscopy Procedures (Hardeep Singh Kalsi, Martin R. Carby)....Pages 301-312 Imaging of Lung Transplantation (Jitesh Ahuja, Siddhartha G. Kapnadak, Sudhakar Pipavath)....Pages 313-326 Front Matter ....Pages 327-327 New Horizons in Lung Transplantation (Pablo Gerardo Sanchez, Dustin M. Walters, Michael S. Mulligan)....Pages 329-344 Gaps and Future Directions in Lung Transplantation (Keith C. Meyer, Ganesh Raghu)....Pages 345-359 Back Matter ....Pages 361-371