Arterial Chemoreceptors: New Directions and Translational Perspectives

Description

This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017). Each article contains original data and represents up-to-date information concerning the carotid body and oxygen sensing in health and disease. This volume is a required text for all researchers in the field of arterial chemoreception and will provide a valuable reference source for years to come. Front Matter ....Pages i-xxix O2/CO2: Biological Detection to Homeostatic Control (Robert S. Fitzgerald)....Pages 1-12 What Is the Point of the Peak? Assessing Steady-State Respiratory Chemoreflex Drive in High Altitude Field Studies (Christina D. Bruce, Gary Saran, Jamie R. Pfoh, Jack K. Leacy, Shaelynn M. Zouboules, Carli R. Mann et al.)....Pages 13-23 Hypoxia Regulates MicroRNA Expression in the Human Carotid Body (Souren Mkrtchian, Kian Leong Lee, Jessica Kåhlin, Anette Ebberyd, Lorenz Poellinger, Malin Jonsson Fagerlund et al.)....Pages 25-33 TASK-1 (K2P3) and TASK-3 (K2P9) in Rabbit Carotid Body Glomus Cells (Dawon Kang, Jiaju Wang, James O. Hogan, Donghee Kim)....Pages 35-41 Molecular Characterization of Equilibrative Nucleoside Transporters in the Rat Carotid Body and Their Regulation by Chronic Hypoxia (Shaima Salman, Colin A. Nurse)....Pages 43-50 Mitochondrial Complex I Dysfunction and Peripheral Chemoreflex Sensitivity in a FASTK-Deficient Mice Model (Angela Gomez-Niño, Inmaculada Docio, Jesus Prieto-Lloret, Maria Simarro, Miguel A. de la Fuente, Asuncion Rocher)....Pages 51-59 Topical Application of Connexin43 Hemichannel Blocker Reduces Carotid Body-Mediated Chemoreflex Drive in Rats (David C. Andrade, Rodrigo Iturriaga, Camilo Toledo, Claudia M. Lucero, Hugo S. Díaz, Alexis Arce-Álvarez et al.)....Pages 61-68 Proinflammatory Cytokines in the Nucleus of the Solitary Tract of Hypertensive Rats Exposed to Chronic Intermittent Hypoxia (María Paz Oyarce, Rodrigo Iturriaga)....Pages 69-74 Central Hypoxia Elicits Long-Term Expression of the Lung Motor Pattern in Pre-metamorphic Lithobates Catesbeianus (Tara A. Janes, Richard Kinkead)....Pages 75-82 Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia (Nuno R. Coelho, Clara G. Dias, M. João Correia, Patrícia Grácio, Jacinta Serpa, Emília C. Monteiro et al.)....Pages 83-88 Adenosine Mediates Hypercapnic Response in the Rat Carotid Body via A2A and A2B Receptors (Joana F. Sacramento, Bernardete F. Melo, Sílvia V. Conde)....Pages 89-93 Acute Effects of Systemic Erythropoietin Injections on Carotid Body Chemosensory Activity Following Hypoxic and Hypercapnic Stimulation (David C. Andrade, Rodrigo Iturriaga, Florine Jeton, Julio Alcayaga, Nicolas Voituron, Rodrigo Del Rio)....Pages 95-102 Carotid Body Dysfunction in Diet-Induced Insulin Resistance Is Associated with Alterations in Its Morphology (Eliano Dos Santos, Joana F. Sacramento, Bernardete F. Melo, Sílvia V. Conde)....Pages 103-108 Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Pre-clinical Mouse Model (Ying-Jie Peng, Xiuli Zhang, Jayasri Nanduri, Nanduri R. Prabhakar)....Pages 109-114 Role of Estradiol Receptor Beta (ERβ) on Arterial Pressure, Respiratory Chemoreflex and Mitochondrial Function in Young and Aged Female Mice (Sofien Laouafa, Damien Roussel, François Marcouiller, Jorge Soliz, Aida Bairam, Vincent Joseph)....Pages 115-127 Chronic Heart Failure Abolishes Circadian Rhythms in Resting and Chemoreflex Breathing (Robert Lewis, Bryan T. Hackfort, Harold D. Schultz)....Pages 129-136 High Fat Feeding in Rats Alters Respiratory Parameters by a Mechanism That Is Unlikely to Be Mediated by Carotid Body Type I Cells (Ryan J. Rakoczy, Richard L. Pye, Tariq H. Fayyad, Joseph M. Santin, Barbara L. Barr, Christopher N. Wyatt)....Pages 137-142 Leptin in the Commissural Nucleus Tractus Solitarii Increases the Glucose Responses to Carotid Chemoreceptors Activation by Cyanide (Mónica Lemus, Cynthia Mojarro, Sergio Montero, Valery Melnikov, Mario Ramírez-Flores, Elena Roces de Álvarez-Buylla)....Pages 143-149 Chronic Intermittent Hypoxia in Premature Infants: The Link Between Low Fat Stores, Adiponectin Receptor Signaling and Lung Injury (Na-Young Kang, Julijana Ivanovska, Liran Tamir-Hostovsky, Jaques Belik, Estelle B. Gauda)....Pages 151-157 Myo-inositol Effects on the Developing Respiratory Neural Control System (Peter M. MacFarlane, Juliann M. Di Fiore)....Pages 159-166 Adrenal Medulla Chemo Sensitivity Does Not Compensate the Lack of Hypoxia Driven Carotid Body Chemo Reflex in Guinea Pigs (Elena Olea, Elvira Gonzalez-Obeso, Teresa Agapito, Ana Obeso, Ricardo Rigual, Asuncion Rocher et al.)....Pages 167-174 Back Matter ....Pages 175-187