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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume include the role and distribution of retinoic acid during CNS development, the role of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family, the biology of cortical granules, acetylcholinesterase genes in the nematode caenorhabditis elegans, and reciprocal regulation of endothelin-1 and nitric oxide. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. *The Role and Distribution of Retinoic Acid during CNS Development*The Roles of Receptor-Associated Protein (RAP) as a Molecular Chaperone for Members of the LDL Receptor Family*The Biology of Cortical Granules*Acetylcholinesterase Genes in the Namatode Caenorhabditis elegans*Receprocal Regulation of Endothelin-1 and Nitric Oxide: Relevance in the Physiology and Pathology of the Cardiovascular System