Oxford Textbook of Cancer Biology

Description

Cover Oxford Textbook of Cancer Biology Copyright Contents Abbreviations Contributors SECTION I The multicellular organism 1. The multicellular organism and cancer 2. DNA repair and genome integrity 3. Evolution and cancer SECTION II The aetiology of cancer 4. Genetics and genetic instability in cancer 5. Epigenetics 6. Viral carcinogenesis—an overview 7. Chemical carcinogens 8. Radiation as a carcinogen SECTION III How the cancer cell works 9. Growth factors and associated signalling pathways in tumour progression and in cancer treatment 10. Hormones and cancer 11. Oncogenesis and tumour suppression 12. The signalling pathways in cancer 13. Cell cycle control 14. Cancer and cell death 15. Telomerase and immortalization 16. Cancer metabolism 17. Chaperones and protein quality control in the neoplastic process 18. Oxygen and cancer: The response to hypoxia 19. Invasion, metastasis, and tumour dormancy 20. Cancer stem cells SECTION IV Cancer microenvironment 21. Cancer-​associated stroma 22. Blood vessels and cancer 23. Cancer immunology SECTION V Global vision of cancer 24. Molecular profiling in cancer research and personalized medicine 25. Proteomics and metabolomics applications in cancer biology 26. Cancer systems biology: From molecular profiles to pathways, signalling networks, and therapeutic vulnerabilities 27. Cancer biology through immunohistology SECTION VI The biology of cancer treatment 28. Principles of chemotherapy 29. Immunotherapy and tumour resistance to immune-​mediated control and elimination 30. Biological effect of radiotherapy on cancer cells SECTION VII Conclusions 31. Benign tumours: The forgotten neoplasms 32. Conclusions: Cancer biology, a moveable feast Index