ENGLISH

HIV and Tuberculosis: A Formidable Alliance

By Irini Sereti , Gregory P. Bisson , Graeme Meintjes

Book information

Publisher
Springer International Publishing
Year
2019
ISBN
978-3-030-29107-5, 978-3-030-29108-2
Language
english
Format
PDF
Filesize
6 MB (6193554 bytes)
Edition
1st ed. 2019
Pages
X, 347\347
Time added
2020-02-08 04:41:46
Biomedicine; Virology; Infectious Diseases; Immuno

Description

Globally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for one in every three HIV deaths and over 300,000 in 2017 alone. The HIV epidemic has undermined tuberculosis-control efforts in many countries around the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities. The past two decades have yielded thousands of research publications and review articles on HIV-associated TB. HIV and Tuberculosis: A Formidable Alliance consolidates this massive amount of data into a single resource. With contributions from myriad disciplines, including epidemiology, immunology, public health, and clinical medicine, this book provides well-rounded and thorough coverage that will appeal to researchers and clinicians alike. Front Matter ....Pages i-x Overview of the HIV-Associated Tuberculosis Epidemic (Constance A. Benson)....Pages 1-7 Epidemiology of Drug-Susceptible, Drug-Resistant Tuberculosis and HIV in Africa (Kogieleum Naidoo, Nikita Naicker)....Pages 9-23 Modelling the HIV-Associated TB Epidemic and the Impact of Interventions Aimed at Epidemic Control (P. J. Dodd, C. Pretorius, B. G. Williams)....Pages 25-55 Immune Responses to Mycobacterium tuberculosis and the Impact of HIV Infection (Catherine Riou, Cari Stek, Elsa Du Bruyn)....Pages 57-72 Clinical Manifestations of HIV-Associated Tuberculosis in Adults (Sean Wasserman, David Barr, Graeme Meintjes)....Pages 73-97 The Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome (TB-IRIS) (Irini Sereti, Gregory P. Bisson, Graeme Meintjes)....Pages 99-125 Diagnosis of HIV-Associated Tuberculosis (Andrew D. Kerkhoff, Adithya Cattamanchi)....Pages 127-159 Recent Advances in the Treatment of Latent Tuberculosis Infection Among Adults Living with HIV Infection (April C. Pettit, Timothy R. Sterling)....Pages 161-179 Treatment of Drug-Sensitive Tuberculosis in Persons with HIV (Alice K. Pau, Safia Kuriakose, Kelly E. Dooley, Gary Maartens)....Pages 181-202 Drug-Resistant Tuberculosis and HIV (Sara C. Auld, Neel R. Gandhi, James C. M. Brust)....Pages 203-237 Co-treatment of Tuberculosis and HIV: Pharmacologic Considerations (Ethel D. Weld, Alice K. Pau, Gary Maartens, Kelly E. Dooley)....Pages 239-267 HIV and Tuberculosis in Children (Tonya Arscott-Mills, Ben Marais, Andrew Steenhoff)....Pages 269-294 Neurological TB in HIV (Louise Bovijn, Regan Solomons, Suzaan Marais)....Pages 295-334 Back Matter ....Pages 335-347

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