Hormones in ageing and longevity

Description

This multi-chapter book focuses on one of the hottest topics in ageing research – the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity. Hormones are an excellent system of communication between cells and tissues within an organism, and they coordinate a wide range of processes in biological systems, including neuroendocrine and immunological controls. The book offers insights into the latest significant advances in our understanding of the mechanisms of hormonal signaling that control a variety of processes involved in development and ageing. It is divided into four parts: Part I includes a review of the hundred-year history of hormones by the illustrious hormone biochemist Dr. J.R. Tata. Part II presents various chapters on the hormones involved in growth, stress and metabolism, while Part III addresses the hormones controlling cognition and rhythms in ageing processes. Lastly, Part IV discusses the hormones affecting reproduction, immunity and life span. It also explores the use of hormones as pharmaceuticals to maintain health in the elderly. It is a valuable resource for those working in the area of hormone signaling in general and in the field of ageing research in particular. Read more... Abstract: This multi-chapter book focuses on one of the hottest topics in ageing research – the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity. Hormones are an excellent system of communication between cells and tissues within an organism, and they coordinate a wide range of processes in biological systems, including neuroendocrine and immunological controls. The book offers insights into the latest significant advances in our understanding of the mechanisms of hormonal signaling that control a variety of processes involved in development and ageing. It is divided into four parts: Part I includes a review of the hundred-year history of hormones by the illustrious hormone biochemist Dr. J.R. Tata. Part II presents various chapters on the hormones involved in growth, stress and metabolism, while Part III addresses the hormones controlling cognition and rhythms in ageing processes. Lastly, Part IV discusses the hormones affecting reproduction, immunity and life span. It also explores the use of hormones as pharmaceuticals to maintain health in the elderly. It is a valuable resource for those working in the area of hormone signaling in general and in the field of ageing research in particular Front Matter ....Pages i-viii Front Matter ....Pages 1-1 How Hormones, as Ancient Signalling Molecules, Regulate Diverse Biological Processes Through Evolution (Jamshed R. Tata)....Pages 3-20 Somatotropic Axis’ Role in Ageing and Longevity Could Depend on Life-History Strategies of Species (Éric Le Bourg)....Pages 21-33 Front Matter ....Pages 35-35 Glucocorticoid Hormones in Aging (Banteiskhem Kharwanlang, Ramesh Sharma)....Pages 37-55 Zinc, Insulin and IGF-I Interplay in Aging (Marco Malavolta, Francesco Piacenza, Laura Costarelli, Maurizio Cardelli, Lory Santarelli, Eugenio Mocchegiani et al.)....Pages 57-90 Growth Hormone and IGF-1 Axis in Aging and Longevity (Isao Shimokawa)....Pages 91-106 Thyroid Function in Healthy Ageing and Longevity (Naveen Aggarwal, Salman Razvi)....Pages 107-125 TGF-β in Development and Ageing (Harris Pratsinis, Eleni Mavrogonatou, Dimitris Kletsas)....Pages 127-148 Front Matter ....Pages 149-149 Hormones of Hypothalamus in Aging (Gurcharan Kaur, Jyoti Parkash)....Pages 151-165 Environmental and Physiological Cues on the Hypothalamus During Aging (Jan O. Nehlin)....Pages 167-208 Melatonin in Healthy Aging and Longevity (Rüdiger Hardeland)....Pages 209-242 Hormones in Clock Regulation During Ageing (Anita Jagota, Neelesh Babu Thummadi)....Pages 243-265 Front Matter ....Pages 267-267 Estrogens in Ageing (Mahendra K. Thakur, V. Paramanik)....Pages 269-289 Cytokines and Aging (Pramod C. Rath)....Pages 291-310 Plant Hormone Cytokinins for Modulating Human Aging and Age-Related Diseases (Jiří Voller, Barbara Maková, Alena Kadlecová, Gabriel Gonzalez, Miroslav Strnad)....Pages 311-335 Back Matter ....Pages 337-338