ENGLISH

Molecular Mechanisms of Neurodegenerative Diseases (Contemporary Clinical Neuroscience)

Book information

Year
2001
ISBN
9780896038042, 9781592590063, 0896038041
Open Library ID
OL9344369M
Language
english
Format
PDF
Filesize
2 MB (1915543 bytes)
Edition
1st
Pages
410\426
Topic
Medicine Neurology
Time added
2011-06-04 13:46:07

Description

Marie-Fran?oise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.

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