Exercise for Cardiovascular Disease Prevention and Treatment: From Molecular to Clinical, Part 2

Description

The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc. Front Matter ....Pages i-vi Front Matter ....Pages 1-1 Exercise Benefits Coronary Heart Disease (Lei Wang, Dongmei Ai, Ning Zhang)....Pages 3-7 Exercise Exerts Its Beneficial Effects on Acute Coronary Syndrome: Clinical Evidence (Zhuyuan Liu, Huanyu Gu, Qiying Dai, Hongbao Wang, Jianhua Yao, Lei Zhou)....Pages 9-29 Exercise-Based Rehabilitation for Heart Failure: Clinical Evidence (Rongjing Ding)....Pages 31-49 The Benefits of Exercise Training on Aerobic Capacity in Patients with Heart Failure and Preserved Ejection Fraction (Danilo Marcelo Leite do Prado, Enéas Antônio Rocco)....Pages 51-64 Hypertension and Exercise Training: Evidence from Clinical Studies (Ivana C. Moraes-Silva, Cristiano Teixeira Mostarda, Antonio Carlos Silva-Filho, Maria Claudia Irigoyen)....Pages 65-84 Effects of Exercise on Arrhythmia (and Viceversa): Lesson from the Greek Mythology (Caterina Lambiase, Silvia Macerola, Giovanna Bosco, Elisa Messina, Pasquale Franciosa)....Pages 85-93 Exercise and Congenital Heart Disease (Junnan Wang, Bin Liu)....Pages 95-101 The Positive Effects of Exercise in Chemotherapy-Related Cardiomyopathy (Cavarretta Elena, Mastroiacovo Giorgio, Lupieri Annik, Frati Giacomo, Peruzzi Mariangela)....Pages 103-129 Clinical Evidence of Exercise Benefits for Stroke (Peipei Han, Wen Zhang, Li Kang, Yixuan Ma, Liyuan Fu, Liye Jia et al.)....Pages 131-151 Evidence on Exercise Training in Pulmonary Hypertension (Abraham Samuel Babu, Ross Arena, Norman R. Morris)....Pages 153-172 Peripheral Vascular Disease: The Beneficial Effect of Exercise in Peripheral Vascular Diseases Based on Clinical Trials (Basant M. Elnady, Ayman Saeed)....Pages 173-183 Front Matter ....Pages 185-185 The IGF1-PI3K-Akt Signaling Pathway in Mediating Exercise-Induced Cardiac Hypertrophy and Protection (Kate L. Weeks, Bianca C. Bernardo, Jenny Y. Y. Ooi, Natalie L. Patterson, Julie R. McMullen)....Pages 187-210 NO Signaling in the Cardiovascular System and Exercise (Tiago Fernandes, Camila V. Gomes-Gatto, Noemy P. Pereira, Yahya R. Alayafi, Vander J. das Neves, Edilamar M. Oliveira)....Pages 211-245 C/EBPB-CITED4 in Exercised Heart (Shengguang Ding, Tianyi Gan, Meiyi Song, Qiying Dai, Haitao Huang, Yiming Xu et al.)....Pages 247-259 MicroRNAs Mediate Beneficial Effects of Exercise in Heart (Yihua Bei, Lichan Tao, Dragos Cretoiu, Sanda Maria Cretoiu, Junjie Xiao)....Pages 261-280 Exercise Training and Epigenetic Regulation: Multilevel Modification and Regulation of Gene Expression (Ursula Paula Renó Soci, Stephano Freitas Soares Melo, João Lucas Penteado Gomes, André Casanova Silveira, Clara Nóbrega, Edilamar Menezes de Oliveira)....Pages 281-322 Exercise-Induced Mitochondrial Adaptations in Addressing Heart Failure (Jubert Marquez, Jin Han)....Pages 323-332 Exosomes Mediate the Beneficial Effects of Exercise (Yangxin Li, Chaoshan Han, Juanjuan Wang, Jin Zhou, Chun Liang, Kasturi Ranganna et al.)....Pages 333-353 Front Matter ....Pages 355-355 Exercise Dosing and Prescription-Playing It Safe: Dangers and Prescription (Lei Wang, Dongmei Ai, Ning Zhang)....Pages 357-387