Bioinformatics

Description

InTeOp – 2012, 335 pagesISBN: 9535108788, 9789535108788The book introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here.This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis.Contents:PrefaceSection 1 Analysis of Biological NetworksHierarchical Biological Pathway Data Integration and MiningInvestigation on Nuclear Transport of Trypanosoma brucei: An in silico ApproachSystemic Approach to the Genome Integration Process of Human LentivirusSection 2 Sequence AnalysisSeqAnt 2012: Recent Developments in Next-Generation Sequencing AnnotationSection 3 High-Performance ComputingTowards a Hybrid Federated Cloud Platform to Efficiently Execute BioinformaticsWorkflowsHardware Accelerated Molecular Docking: A SurveySection 4 Molecular ModelingIncorporating Molecular Dynamics Simulations into Rational Drug Design: A Case Study on Influenza a NeuraminidasesUsing Molecular Modelling to Study Interactions Between Molecules with Biological ActivitySection 5 Structural BioinformaticsOn the Assessment of Structural Protein Models with ROSETTA-Design and HMMer: Value, Potential and LimitationsSection 6 Intelligent Data AnalysisBacterial Promoter Features Description and Their Application on E. coli in silico Prediction and Recognition ApproachesComputational Approaches for Designing Efficient and Specific siRNAsNovel microRNA Cloning Using BioinformaticsEnsemble Clustering for Biological DatasetsResearch on Pattern Matching with Wildcards and Length Constraints: Methods and Completeness