ENGLISH

Gene Therapy

By Mauro Giacca (auth.)

Book information

Publisher
Springer-Verlag Mailand
Year
2010
ISBN
978-88-470-1642-2, 978-88-470-1643-9
DOI
10.1007/978-88-470-1643-9
Language
english
Format
PDF
Filesize
4 MB (4335195 bytes)
Edition
1
Pages
303\318
Orientation
yes
Scanned
yes
Time added
2013-10-27 04:58:40
Gene Therapy; Molecular Medicine; Internal Medicin

Description

This book presents to the reader a comprehensive and detailed, yet easily accessible, description of the whole field of gene therapy. It covers topics ranging from vector development to the results of the most recent clinical trials. It includes descriptions of lentiviral and AAV vector development, of therapeutic gene selection (including siRNAs, shRNAs, and microRNAs), and of the most recent clinical applications of gene therapy for diseases of the eye, the cardiovascular system, and the central nervous system. Of note, the book only considers conditions for which transfer of genetic material has already progressed to clinical applications or is close to doing so. The language is plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical fields, whenever technical descriptions are required these are provided. Readers will include graduate students in the life sciences area in their final years of study, PhD students, and medical doctors specializing in different fields of internal and specialist medicine, in addition to research scientists working in various areas of current biomedical research.

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