ENGLISH

Amino-Acid Homopolymers Occurring in Nature

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2010
ISBN
3642124526, 9783642124525
DOI
10.1007/978-3-642-12453-2
Language
english
Format
PDF
Filesize
3 MB (3169443 bytes)
Series
Microbiology Monographs 15
Edition
1
Pages
250\173
Time added
2011-06-04 13:46:07

Description

Microorganisms are capable of producing a wide variety of biopolymers. Homopolymer peptides, which are made up of only a single type of amino acid, are far less ubiquitous. The only two amino-acid homopolymers known to occur in nature are presented in this volume. Poly-epsilon-L-lysine is a polycationic peptide and exhibits antimicrobial activity against a wide spectrum of microorganisms. It is both safe and biodegradable and is therefore used as a food preservative in several countries. In addition, there has been great interest in medical and other applications of poly-lysine and its derivatives. In contrast, poly-gamma-glutamic acid is an unusual anionic polypeptide. It is also water soluble, biodegradable, edible, non-toxic and non-immunogenic and can be chemically modified to introduce various drugs. These features are very useful for pharmaceutical and biomedical applications. Poly-glutamic acid is also a highly attractive as food ingredient.

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