ENGLISH

Antibody-Drug Conjugates

By Ingrid Sassoon , Véronique Blanc (auth.) , Laurent Ducry (eds.)

Book information

Publisher
Humana Press
Year
2013
ISBN
978-1-62703-540-8, 978-1-62703-541-5
DOI
10.1007/978-1-62703-541-5
Language
english
Format
PDF
Filesize
5 MB (4882768 bytes)
Series
Methods in Molecular Biology 1045
Edition
1
Pages
317\315
Orientation
yes
Scanned
yes
Time added
2013-08-10 19:24:12
Pharmacology/Toxicology; Oncology

Description

Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs. In Antibody-Drug Conjugates, expert researchers provide detailed protocols for many of the key ADC techniques necessary for working in the field. These chapters and methodologies are aimed at the key tasks necessary to identify a suitable target, properly design the mAb, the linker and the payload, as well as to conjugate them in a reproducible and scalable fashion. Written in the highly successful Methods in Molecular Biology™ format, these detailed chapters include the kind of practical implementation advice that guarantees quality results. Authoritative and timely, Antibody-Drug Conjugates aims to further drive ADC development and thus help toward improving cancer treatments of the future.

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