Therapeutic Advances in Thrombosis, Second Edition

Description

Managing patients with thrombotic vascular disease is complex and challenging:Ischemic vascular disease remains a complicated interplay of atherosclerosis and thrombosis?even with the evolution in our understanding of the pathobiology of thrombosis.There has been tremendous growth in therapeutic options which are quickly finding their place in daily practice, including a remarkable expansion in the number of intravenous and oral antithrombotic agents and new antiplatelet agentsNow more than ever, all cardiologists, hematologists, and specialists in vascular medicine, as well as other professionals, such as hospital pharmacists, who deal with prognosis and intervention in preventing thrombosis, need a resource that distills current knowledge of this important subject.Written and edited by today’s leading international, Therapeutic Advances in Thrombosis, 2e provides physicians with the very latest in medical and surgical advances in antithrombotic therapies. With this comprehensively updated edition you get:Coverage of virtually all aspects of venous and arterial thrombotic disease and the corresponding therapiesStrategies to manage specific clinical conditions and how to tailor treatment to individual patient needsUpdated chapters covering thrombolysis in ST-elevated myocardial infarctions; thrombosis in patients with diabetes, pregnancy, and renal dysfunctionSpecial emphasis on the pharmacology of novel anticoagulants and their practical use in venous thromboembolism and atrial fibrillation.Plus, all chapters fully explore clinical trial designs and outcomes for particular treatment therapies, as well as contain the relevant ACC/AHA/ESC guidelines, so you can confidently apply what you learn.Content: Chapter 1 Arterial Thrombosis: A Brief Overview (pages 1–11): Lina Badimon and Valentin FusterChapter 2 Aspirin (pages 12–25): Carlo PatronoChapter 3 Platelet ADP P2Y12 Inhibitors: Thienopyridines (pages 26–46): Joseph D. Foley and David J. MoliternoChapter 4 Platelet ADP P2Y12 Inhibitors: Nonthienopyridines (pages 47–61): Joseph D. Foley and David J. MoliternoChapter 5 Cilostazol and Dipyridamole: More than Weak Inhibition of Platelets (pages 62–70): Wolfgang G. EisertChapter 6 Interrelationship of Thrombin and Platelets: The Protease Activated Receptor?1 (pages 71–86): Matthew E. Wiisanen and David J. MoliternoChapter 7 Glycoprotein IIb/IIIa Inhibitors (pages 87–110): Marco Valgimigli and Elisa CangianoChapter 8 Unfractionated Heparin and Low Molecular Weight Heparin in Ischemic Heart Disease (pages 111–127): Zafar Iqbal, Omar Hasan and Marc CohenChapter 9 Pentasaccharide Derivatives (pages 128–149): Antonio Gutierrez, Pierluigi Tricoci and John H. P. AlexanderChapter 10 Intravenous Direct Thrombin Inhibitors (pages 150–165): Femi Philip and A. Michael LincoffChapter 11 Vitamin K Antagonists (pages 166–179): Freek W. A. VerheugtChapter 12 Oral Direct Thrombin Inhibitors and Oral Factor Xa Inhibitors (pages 180–188): Steen Husted and Lars WallentinChapter 13 Thrombolytic Therapy and Concomitant Antithrombotic Therapies (pages 189–204): Peter R. Sinnaeve and Frans J. Van de WerfChapter 14 Antithrombotic Therapy in ST?Segment Elevation Myocardial Infarction (pages 205–212): Kurt Huber, Raffaele De Caterina and Steen Dalby KristensenChapter 15 Antithrombotic Therapy in Non–ST?Segment Elevation Acute Coronary Syndromes (pages 213–235): Georgios J. Vlachojannis, Vijayalakshmi Kunadian, Joseph M. Sweeny and Roxana MehranChapter 16 Antithrombotic Strategies in Patients Undergoing Elective Percutaneous Coronary Intervention (pages 236–245): Sunil V. Rao and E. Magnus OhmanChapter 17 Antithrombotic Management in Patients with Prosthetic Valves (pages 246–271): Eric G. Butchart and Raffaele De CaterinaChapter 18 Stroke: Thrombolysis and Antithrombotic Therapy (pages 272–284): L. Creed Pettigrew and Michael R. DobbsChapter 19 Atrial Fibrillation: Current and Forthcoming Antithrombotic Therapies (pages 285–305): Raffaele De Caterina and Giulia RendaChapter 20 Venous Thromboembolism: Pathophysiology, Diagnosis, and Prophylaxis (pages 306–316): Marco P. Donadini, Walter Ageno and Alexander G. TurpieChapter 21 Antithrombotic Therapy in Venous Thrombosis and Pulmonary Embolism (pages 317–326): Marcello Di Nisio and Harry R. BullerChapter 22 Prevention and Treatment of Venous and Arterial Thrombosis in Patients with Specific Conditions: Diabetes, Hypercoagulable States, Pregnancy, and Renal Insufficiency (pages 327–356): Meyer Michel Samama, Jacqueline Conard and Grigoris GerotziafasChapter 23 Genetics of the Response to Antithrombotic Drugs and the Need for Monitoring (pages 357–377): Jean?Philippe Collet, Gilles Montalescot and Jean?Sebastien Hulot