ENGLISH

Early Nutrition and Lifestyle Factors: Effects on First Trimester Placenta

By Asim K. Duttaroy , Sanjay Basak (auth.)

Book information

Publisher
Springer International Publishing
Year
2016
ISBN
978-3-319-38802-1, 978-3-319-38804-5
DOI
10.1007/978-3-319-38804-5
Language
english
Format
PDF
Filesize
2 MB (2390694 bytes)
Edition
1
Pages
X, 159\166
Time added
2016-11-20 09:00:00
Human Physiology;Medical Biochemistry;Nutrition;Gy

Description

This book highlights the impact of nutrients on early placentation processes and their relevance for fetal growth and pregnancy outcome.​ The role of maternal nutrition on fetal growth and development has been evidenced in many epidemiological studies that included infamous Dutch famine, Helsinki Birth cohort and others. Fetal programming hypothesis states that the nutritional and other environmental conditions under which an individual develops from pre-conception to birth has a major impact on the future health of the newborn child. The developmental environment of the fetus is primarily dependent on two major factors that are maternal nutritional state (excess/low/imbalance) and placental function. Placentation is characterized by the extensive remodeling of the maternal uterine vasculature producing low-resistance blood vessels that facilitate the exchange of nutrients and wastes between the mother and the fetus. Cellular and molecular mechanisms involved in human placental blood vessel formation, which are now well established, are discussed.

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