ENGLISH

Cytotoxic Drug Resistance Mechanisms (Methods in Molecular Medicine)

By Robert Brown , Uta Böger-Brown

Book information

Publisher
Humana Press
Year
2010
ISBN
1617370932, 9781617370939
Language
english
Format
PDF
Filesize
1 MB (1266277 bytes)
Edition
Softcover reprint of hardcover 1st ed. 1999
Pages
235\235
Time added
2012-02-04 16:00:00

Description

Leading clinical and laboratory scientists describe cutting-edge methods for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumors. The protocols contain detailed instructions and extensive troubleshooting tips that allow researchers effectively to study a wide variety of drug resistance mechanisms, including aspects of drug-induced cell death, drug uptake/efflux, drug metabolism, and DNA repair. Each method is designed to help identify the correlation between molecular and biochemical data and the clinical responses of the patient. Cytotoxic Drug Resistance Mechanisms illuminates all the clinically relevant mechanisms used as markers of the biological response to anticancer biotherapeutics today.

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