Molecular Evolution on Rugged Landscapes : Protein, RNA, and the Immune System (Volume IX)

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Content: Cover Half Title Title Page Copyright Page Preface Table of Contents Rugged Landscapes and Evolution Optimization on Rugged Landscapes A Spin-Glass Model of Evolution What Can Physics Do For Biology? Optimization of RNA Structure and Propterties Somatic Evolution of Antibody Variable-Region Genes & Maturation of the Immune Response Affinity Maturation: A Retrospective View Maturation through Hypermutation and Selection Affinity Maturation on Rugged Landscapes Maturation of the Humoral Immune Response: A Neo-Darwinian Process? The NK Model of Rugged Fitness Landscapes and Its Application to Maturation of the Immune ResponseUse of Antibodies as Molecular Mimics to Probe Intermolecular Interaction Landscapes Affinity Maturation and Learning in Immune Networks Auto-Anti-Idiotype and Antigen as Selective Factors Driving B-Cell Affinity Maturation in the Immune System Somatic Mutation and the Antibody Repertoire: A Computational Model of Shape Space Applied Molecular Evolution Evolution of Proteins from Random Sequences: A Model for the Protein Sequence Space and an Experimental Approach. Studies in the Evolution of Biological Activity from Random SequencesThe Catalytic Potential of RNA Origin of Life Models Dynamics of Autocatalytic Reaction Networks Index.