ENGLISH

Translating Molecular Biomarkers into Clinical Assays : Techniques and Applications

By Russell Weiner , Marian Kelley (eds.)

Book information

Publisher
Springer International Publishing
Year
2016
ISBN
978-3-319-40792-0, 978-3-319-40793-7
DOI
10.1007/978-3-319-40793-7
Language
english
Format
PDF
Filesize
3 MB (2980176 bytes)
Series
AAPS Advances in the Pharmaceutical Sciences Series 21
Edition
1
Pages
XIII, 212\217
Time added
2016-11-20 09:00:00
Pharmaceutical Sciences/Technology;Pharmacy

Description

This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.

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