Practical Applications of Computational Biology and Bioinformatics, 12th International Conference

Description

This book introduces the latest international research in the fields of bioinformatics and computational biology. It includes various studies in the area of machine learning in bioinformatics, systems biology, omics data analysis and mining, biomedical applications and sequences, which were selected by an international committee and presented at the 12th International Conference on Practical Applications of Computational Biology & Bioinformatics held in Toledo in June 2018. Front Matter ....Pages i-xiii A Hybrid of Simple Constrained Artificial Bee Colony Algorithm and Flux Balance Analysis for Enhancing Lactate and Succinate in Escherichia Coli (Mei Kie Hon, Mohd Saberi Mohamad, Abdul Hakim Mohamed Salleh, Yee Wen Choon, Muhammad Akmal Remli, Mohd Arfian Ismail et al.)....Pages 1-8 Parameter Estimation of Essential Amino Acids in Arabidopsis thaliana Using Hybrid of Bees Algorithm and Harmony Search (Mei Yee Aw, Mohd Saberi Mohamad, Chuii Khim Chong, Safaai Deris, Muhammad Akmal Remli, Mohd Arfian Ismail et al.)....Pages 9-16 In Silico Modeling and Simulation Approach for Apoptosis Caspase Pathways (Pedro Pablo González-Pérez, Maura Cárdenas-García)....Pages 17-26 Molecular Dynamic Simulations Suggest that P152R Mutation Within MeCP2 Can Lead to Higher DNA Binding Affinity and Loss of Selective Binding to Methylated DNA (Dino Franklin)....Pages 27-34 Impact of Genealogical Features in Transthyretin Familial Amyloid Polyneuropathy Age of Onset Prediction (Maria Pedroto, Alípio Jorge, João Mendes-Moreira, Teresa Coelho)....Pages 35-42 Feature Selection and Polydispersity Characterization for QSPR Modelling: Predicting a Tensile Property (Fiorella Cravero, Santiago Schustik, María Jimena Martínez, Carlos D. Barranco, Mónica F. Díaz, Ignacio Ponzoni)....Pages 43-51 Methods of Creating Knowledge Graph by Linking Biological Databases (Nazar Zaki, Chandana Tennakoon, Hany Al Ashwal, Alanoud Al Jaberi, Amel Al Ameri)....Pages 52-62 QSAR Modelling for Drug Discovery: Predicting the Activity of LRRK2 Inhibitors for Parkinson’s Disease Using Cheminformatics Approaches (Víctor Sebastián-Pérez, María J. Martínez, Carmen Gil, Nuria E. Campillo, Ana Martínez, Ignacio Ponzoni)....Pages 63-70 Improving the Use of Deep Convolutional Neural Networks for the Prediction of Molecular Properties (Niclas Ståhl, Göran Falkman, Alexander Karlsson, Gunnar Mathiason, Jonas Boström)....Pages 71-79 An Analysis of Symmetric Words in Human DNA: Adjacent vs Non-adjacent Word Distances (Carlos A. C. Bastos, Vera Afreixo, João M. O. S. Rodrigues, Armando J. Pinho)....Pages 80-87 A Bioinformatics Protocol for Quickly Creating Large-Scale Phylogenetic Trees (Hugo López-Fernández, Pedro Duque, Sílvia Henriques, Noé Vázquez, Florentino Fdez-Riverola, Cristina P. Vieira et al.)....Pages 88-96 Deep Learning Analysis of Binding Behavior of Virus Displayed Peptides to AuNPs (Haebom Lee, Jun Jo, Yong Oh Lee, Korkmaz Zirpel Nuriye, Leon Abelmann)....Pages 97-104 Compression of Amino Acid Sequences (Diogo Pratas, Morteza Hosseini, Armando J. Pinho)....Pages 105-113 NET-ASAR: A Tool for DNA Sequence Search Based on Data Compression (Manuel Gaspar, Diogo Pratas, Armando J. Pinho)....Pages 114-122 Can an Integrative SNP Approach Substitute Standard Identification in Comprehensive Case/Control Analyses? (Anna Papiez, Marcin Skrzypski, Amelia Szymanowska-Narloch, Ewa Jassem, Agnieszka Maciejewska, Ryszard Pawlowski et al.)....Pages 123-130 Simple Pattern-only Heuristics Lead to Fast Subgraph Matching Strategies on Very Large Networks (Antonino Aparo, Vincenzo Bonnici, Giovanni Micale, Alfredo Ferro, Dennis Shasha, Alfredo Pulvirenti et al.)....Pages 131-138 In Silico Predictions for Fucoxanthin Production by the Diatom Phaeodactylum Tricornutum (Claudia M. Bauer, Paulo Vilaça, Fernanda Ramlov, Eva Regina de Oliveira, Débora Q. Cabral, Caroline Schmitz et al.)....Pages 139-148 EvoPPI: A Web Application to Compare Protein-Protein Interactions (PPIs) from Different Databases and Species (Noé Vázquez, Sara Rocha, Hugo López-Fernández, André Torres, Rui Camacho, Florentino Fdez-Riverola et al.)....Pages 149-156 A Review on Metabolomics Data Analysis for Cancer Applications (Sara Cardoso, Delora Baptista, Rebeca Santos, Miguel Rocha)....Pages 157-165 A Framework for the Automatic Combination and Evaluation of Gene Selection Methods (Bastien Grasnick, Cindy Perscheid, Matthias Uflacker)....Pages 166-174 Parallel Cellular Automaton Tumor Growth Model (Alberto G. Salguero, Manuel I. Capel, Antonio J. Tomeu)....Pages 175-182 MOSCA: An Automated Pipeline for Integrated Metagenomics and Metatranscriptomics Data Analysis (João Carlos Sequeira, Miguel Rocha, Maria Madalena Alves, Andreia Ferreira Salvador)....Pages 183-191 Metabolite Integration Pipeline for the Improvement of Human Metabolic Models (Vítor Vieira, Jorge Ferreira, Ruben Rodrigues, Miguel Rocha)....Pages 192-199 A Genetic Programming Approach Applied to Feature Selection from Medical Data (José A. Castellanos-Garzón, Juan Ramos, Yeray Mezquita Martín, Juan F. de Paz, Ernesto Costa)....Pages 200-207 A DNA Sequence Corpus for Compression Benchmark (Diogo Pratas, Armando J. Pinho)....Pages 208-215 17α-Ethinylestradiol Analysis of Endo- and Exometabolome of Ulva lactuca (Chlorophyta) by 1H-NMR Spectroscopy and Bioinformatics Tools (Debora Cabral, Sara Cardoso, Silvana Rocco, Maurício Sforça, Simone Fanan Hengeltraub, Cláudia Bauer et al.)....Pages 216-223 Back Matter ....Pages 225-226