The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

Description

The most encyclopedic book on the pancreas - providing clear guidance for practicing clinicians & surgeons In the past decade, extraordinary developments in diagnostic and therapeutic radiology and endoscopy have been coupled with major advances in surgical techniques and basic sciences. As a result the management of pancreatic disorders is now handled by a multidisciplinary team. This book shows you how to achieve superior patient management by taking the team approach to in-hospital care. For all known pancreatic disorders, it details the latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology. The Editor and author team are leading pancreatologists of high international repute and they present global best-practice using the newest diagnosis and treatment principles. A timely section on early and late outcome data considers the benefits of management including chemotherapy and immune therapy. Carefully incorporating the latest evidence based data, the book also discusses early diagnosis, limited surgical treatment, oncology, treatment results and the option of transplantation. This new edition contains more than 400 illustrations, line drawings and radiographs to provide a step-by-step approach to endoscopic techniques and surgical procedures. With The Pancreas, Second Edition, you can achieve a greater understanding of the principles of surgical treatment in one reference point.Content: Chapter 1 Definitions of Pancreatic Diseases and their Complications (pages 1–6): David C. Whitcomb and Hans G. BegerChapter 2 The History of the Pancreas (pages 7–41): Irvin M. Modlin, Manish C. Champaneria, Anthony K. C. Chan, Mark Kidd and Geeta N. EickChapter 3 Development of the Pancreas and Related Structures (pages 42–49): Brian LewisChapter 4 Anatomy and Fine Structure (pages 50–57): Dale E. BockmanChapter 5 Congenital and Inherited Anomalies (pages 58–68): Martin Zenker and Markus M. LerchChapter 6 Physiology of Acinar Cell Secretion (pages 69–77): Ole H. PetersenChapter 7 Physiology of Duct Cell Secretion (pages 78–90): Min Goo Lee and Shmuel MuallemChapter 8 Physiology of Experimental Pancreatitis (pages 91–106): Ashok K. Saluja, Vijay P. Singh and Phoebe PhillipsChapter 9 Physiology of Sphincter of Oddi Function (pages 107–112): James ToouliChapter 10 Neurohormonal and Hormonal Control of Exocrine Pancreatic Secretion (pages 113–126): Chung OwyangChapter 11 Regulation of Pancreatic Protein Synthesis and Growth (pages 127–135): Maria Dolors Sans, Stephen J. Crozier and John A. WilliamsChapter 12 Insulo?Acinar Relationship (pages 136–142): Keiko Shiratori and Kyoko ShimizuChapter 13 Etiopathogenesis and Epidemiology of Alcohol?Induced Acute Pancreatitis (pages 143–153): Minoti V. Apte, Ron C. Pirola and Jeremy S. WilsonChapter 14 Etiology and Epidemiology of Biliary Acute Pancreatitis (pages 154–162): Michael G. T. Raraty and John P. NeoptolemosChapter 15 Acute Pancreatitis Associated with Congenital Anomalies (pages 163–171): Tracy C. Grikscheit and Andrew L. WarshawChapter 16 Acute Pancreatitis Associated with Metabolic, Infectious, and Drug?Related Diseases (pages 172–183): Stefan Turi, Matthias Kraft and Markus M. LerchChapter 17 Acute Pancreatitis in Children (pages 184–192): Mark E. Lowe and Veronique D. MorinvilleChapter 18 Understanding of Acute Pancreatitis from Animal Experiments (pages 193–199): Thomas FoitzikChapter 19 Genetic Factors in Acute Pancreatitis (pages 200–208): David C. Whitcomb and Georgios I. PapachristouChapter 20 Histopathology of Acute Pancreatitis (pages 209–213): Gunter KloppelChapter 21 Molecular, Biochemical, and Metabolic Abnormalities of Acute Pancreatitis (pages 214–225): Julia Mayerle, F. Ulrich Weiss, Walter Halangk and Markus M. LerchChapter 22 Clinical Course of Alcoholic Acute Pancreatitis (pages 226–230): Roland H. Pfutzer and Manfred V. SingerChapter 23 Clinical Course and Treatment Principles of Biliary Acute Pancreatitis (pages 231–241): Julia Mayerle, Ashok K. Saluja and Markus M. LerchChapter 24 Clinical Assessment and Biochemical Markers to Objectify Severity and Prognosis (pages 242–254): Bettina M. RauChapter 25 Imaging Acute Edematous–Interstitial and Necrotizing Pancreatitis (pages 255–272): Patrick C. FreenyChapter 26 Treatment of Acute Pancreatitis (pages 273–287): Paul Georg Lankisch, Mark Topazian and Henry J. SchillerChapter 27 Bacterial and Fungal Infections in Necrotizing Pancreatitis: Pathogenesis, Prevention, and Treatment (pages 288–297): Bettina M. Rau and Hans G. BegerChapter 31 Endoscopic Treatment of Necrotizing Pancreatitis (pages 331–335): Stefan Seewald, Salem Omar and Nib SoehendraChapter 33 Management of Fluid Collections in Acute Pancreatitis (pages 344–355): Gregory Stringfellow, Eric Vansonnenberg, Giovanna Casola, Gerhard R. Wittich, Sridhar Shankar and Ray ShamosChapter 34 Management of Pancreatic Fistula in Acute Pancreatitis (pages 356–361): Jens Werner and Markus W. BuchlerChapter 35 Enteral Nutrition and Parenteral Nutrition (pages 362–367): Keiko ShiratoriChapter 36 Long?Term Outcome after Acute Pancreatitis (pages 368–372): Werner Hartwig, Jens Werner and Markus W. BuchlerChapter 28 Indications for Interventional and Surgical Treatment of Acute Pancreatitis (pages 298–307): Thomas E. Clancy and Stanley W. AshleyChapter 29 Surgical Management of Necrotizing Pancreatitis (pages 308–320): Bettina M. Rau, Hans G. Beger, Raymond Aerts, Freddy M. Penninckx, J. Ruben Rodriguez, Carlos Fernandez?del Castillo and Andrew L. WarshawChapter 30 Strategies for Surgical Treatment of Pseudocysts after Acute Pancreatitis (pages 321–330): Antonio Ramos?De la Medina, Kaye M. Reid?Lombardo and Michael G. SarrChapter 32 Minimal?Access Surgical Treatment of Necrotizing Pancreatitis and Pancreatic Abscess (pages 336–343): Saxon Connor, Michael G. T. Raraty, Jonathon Evans and John P. NeoptolemosChapter 37 Chronic Pancreatitis: Consequences of Recurrent Acute Episodes (pages 373–382): Gunter KloppelChapter 38 Fibrogenesis of the Pancreas: The Role of Stellate Cells (pages 383–392): Max G. Bachem, Shaoxia Zhou, Wilhelm Schneiderhan and Marco SiechChapter 39 Epidemiology and Pathophysiology of Alcoholic Chronic Pancreatitis (pages 393–402): Stephen J. Pandol, Aurelia Lugea, Anna S. Gukovskaya and Ilya GukovskyChapter 40 Hereditary Chronic Pancreatitis (pages 403–411): David C. WhitcombChapter 41 Epidemiology and Pathogenesis of Tropical Chronic Pancreatitis (pages 412–419): Rakesh K. TandonChapter 42 Autoimmune Pancreatitis (pages 420–426): Kazuichi OkazakiChapter 43 Cystic Fibrosis?Associated Pancreatitis (pages 427–436): David C. WhitcombChapter 44 Chronic Pancreatitis: A Risk Factor for Cancer? (pages 437–443): Albert B. Lowenfels and Patrick MaisonneuveChapter 45 Molecular understanding of Chronic Pancreatitis (pages 444–453): David C. WhitcombChapter 46 Pain Mechanisms in Chronic Pancreatitis (pages 454–457): Fabio F. di Mola and Pierluigi di SebastianoChapter 47 Clinical and Laboratory Diagnosis of Chronic Pancreatitis (pages 458–468): Julia Mayerle, Peter Simon and Markus M. LerchChapter 48 Contrast?Enhanced Computed Tomography and Magnetic Resonance Imaging (pages 469–476): Hans?Jurgen BrambsChapter 49 Endoscopic Retrograde Cholangiopancreatography, Magnetic Resonance Cholangiopancreatography, and Endoscopic Ultrasound in Chronic Pancreatitis (pages 477–483): Andrew S. Ross and Irving WaxmanChapter 50 Natural Course of Chronic Pancreatitis (pages 484–494): Paul Georg LankischChapter 51 Treatment of Pseudocysts in Chronic Pancreatitis (pages 495–503): Syed A. Ahmad and Jeffrey B. MatthewsChapter 52 Medical Treatment of Chronic Pancreatitis (pages 504–526): Joachim Mossner, Peter Layer, Jutta Keller, Daniel K. Mullady, Stephen J. D. Oi'Keefe, Nathan Howes, William Greenhalf and Michael G. T. RaratyChapter 53 Endoscopic and Interventional Therapy of Chronic Pancreatitis (pages 527–536): Richard A. KozarekChapter 54 Strategies for Surgical Treatment of Chronic Pancreatitis (pages 537–560): Hans G. Beger, Frank Gaunsauge, Michael Schwarz, Bertram Poch, Oscar J. Hines, Howard A. Reber, Bettina M. Rau, Kaye M. Reid?Lombardo, Michael B. Farnell, Michael G. Sarr, Colin J. McKay and Peter WysockiChapter 55 Chronic Pancreatitis: Late Outcome after Medical and Surgical Treatment (pages 561–564): Hans G. Beger and Bertram PochChapter 56 Management of Pancreatic Diabetes Secondary to Chronic Pancreatitis (pages 565–570): Keiko ShiratoriChapter 57 Epidemiology of Pancreatic Cancer (pages 571–582): Nicholas Alexakis, Paula Ghaneh and John P. NeoptolemosChapter 58 Molecular Biological Understanding of Development of Pancreatic Cancer (pages 583–590): Eithne CostelloChapter 59 Familial Pancreatic Cancer (pages 591–600): William Greenhalf, Louis J. Vitone and John P. NeoptolemosChapter 60 Pathology of Exocrine Pancreatic Tumors (pages 601–613): Gunter Kloppel, Bence Sipos and David S. KlimstraChapter 61 Precancerous Lesions (pages 614–620): Roland M. SchmidChapter 62 Role of Endoscopic Ultrasound for Diagnosis and Differential Diagnosis of Neoplastic Lesions (pages 621–628): Drew SchembreChapter 63 Radiologic Diagnosis of Pancreatic Cancer: Computed Tomography and Magnetic Resonance Imaging (pages 629–635): Enrique Lopez Hanninen and Roland FelixChapter 64 Screening of Hereditary Pancreatic Cancer Families (pages 636–642): Christopher Carlson, William Greenhalf and Teresa A. BrentnallChapter 65 Clinical Assessment and Staging of Pancreatic Cancer (pages 643–647): J. Ruben Rodriguez, Andrew L. Warshaw and Carlos Fernandez?Del CastilloChapter 66 Role of Positron Emission Tomography in Diagnosis of Pancreatic Cancer and Cancer Recurrence (pages 648–657): Helmut Friess, Mert Erkan, Jorg Kleeff, Uwe Haberkorn and Markus W. BuchlerChapter 67 Tumor Markers in Pancreatic Malignancies (pages 658–667): Fuyuhiko Motoi, Shin?Ichi Egawa and Seiki MatsunoChapter 68 The Role of Laparoscopy and Peritoneal Cytology in the Management of Pancreatic Cancer (pages 668–677): Kevin Conlon and Paul BalfeChapter 69 Pancreatic Cancer Staging Systems and their Clinical Impact (pages 678–681): Hans G. Beger and Dieter BirkChapter 70 Endoscopic and Interventional Palliation of Pancreatic Cancer (pages 682–688): Todd H. BaronChapter 71 Pancreatic Cancer: Indications for Resection (pages 689–695): Akimasa NakaoChapter 72 Pancreaticoduodenectomy for Pancreatic Cancer: Results after Kausch–Whipple and Pylorus?Preserving Resection (pages 696–706): Ramon E. Jimenez and Andrew L. WarshawChapter 73 Extended Radical Surgery for Pancreatic Cancer (pages 707–713): Jens Werner and Markus W. BuchlerChapter 74 Palliative Pancreaticoduodenectomy: Benefits and Limitations (pages 714–718): Helmut Friess, Jorg Kleeff, Mert Erkan and Markus W. BuchlerChapter 75 Bypass Surgery for Advanced Pancreatic Cancer (pages 719–726): Jurgen Weitz, Peter Kienle and Markus W. BuchlerChapter 76 Neoadjuvant Treatment of Pancreatic Cancer: Borderline?Resectable Disease (pages 727–740): Gauri Varadhachary, Christopher H. Crane, Eric P. Tamm, Huamin Wang, Robert A. Wolff and Douglas B. EvansChapter 77 Adjuvant Chemotherapy in Pancreatic Cancer (pages 741–748): Paula Ghaneh and John P. NeoptolemosChapter 78 Palliative Chemotherapy for Advanced Pancreatic Cancer (pages 749–756): Yu Jo Chua and David CunninghamChapter 79 Management of Cancer Pain (pages 757–764): Sergio Pedrazzoli, Claudio Pasquali, Cosimo Sperti and Francesca AvogaroChapter 80 Role of Radiotherapy in the Treatment of Pancreatic Cancer (pages 765–771): Shilpen Patel, Michael C. Garofalo and William F. RegineChapter 81 Management of Cancer Recurrence (pages 772–775): Helmut Friess, Jorg Kleeff and Markus W. BuchlerChapter 82 Survival and Late Morbidity after Resection of Pancreatic Cancer (pages 776–784): Osamu Ishikawa, Hiroaki Ohigashi, Hidetoshi Eguchi, Yo Sasaki, Terumasa Yamada and Shingi ImaokaChapter 83 Diagnosis of Endocrine Tumors of the Pancreas (pages 785–793): Masayuki ImamuraChapter 84 Islet Cell Tumors (pages 794–801): Peter E. Goretzki and Hans?Dietrich RoherChapter 85 Pancreatic Endocrine Tumors in Multiple Endocrine Neoplasia Syndrome (pages 802–812): Elisabeth Spilcke?Liss, Peter Simon, Markus M. Lerch and Henri WallaschofskiChapter 86 Nonfunctioning Endocrine Tumors (pages 813–817): Hodaka Amano, Tadahiro Takada, Fumihiko Miura, Takehide Asano, Masahiro Yoshida, Naoyuki Toyota, Keita Wada, Takahiro Isaka, Naoyuki Tamura and Kenichiro KatoChapter 87 Surgical Treatment of Endocrine Tumors (pages 818–822): Masayuki ImamuraChapter 88 Treatment of Carcinoids of the Pancreas and Biliary Tract (pages 823–831): Andrea Frilling and Vito CicinnatiChapter 89 Nonsurgical Management of Endocrine Tumors (pages 832–838): Rudolf Arnold and Anja RinkeChapter 90 Liver Transplantation in Advanced Disease of Endocrine Tumors (pages 839–844): Christoph E. Broelsch and Andrea FrillingChapter 91 Long?Term Outcome after Treatment of Endocrine Tumors (pages 845–852): Henning Dralle, Andreas Machens, Michael Brauckhoff and Oliver GimmChapter 92 Periampullary Tumors: Clinical Presentation and Diagnostic Strategy (pages 853–862): Amanda B. Cooper and Keith D. LillemoeChapter 93 Histology of Cancer of the Papilla, Distal Common Bile Duct, and Duodenum (pages 863–869): Hans?Peter FischerChapter 94 Adenoma and Adenocarcinoma of the Ampulla of Vater: Diagnosis and Management (pages 870–879): William R. Brugge and Andrew L. WarshawChapter 95 Endoscopic Treatment of Adenomas of the Ampulla of Vater: Benefits and Limits (pages 880–884): Richard A. Kozarek and L. William TraversoChapter 96 Surgical Treatment of Periampullary Cancer: Early and Late Results after Resection (pages 885–889): Hans G. Beger, Bertram Poch and Bettina M. RauChapter 97 Histology of Cystic Tumors of the Pancreas (pages 891–911): Wataru KimuraChapter 98 Diagnostic Imaging of Cystic Tumors (pages 912–917): Masao Tanaka, Kiichiro Kobayashi, Reiko Tanabe and Koji YamaguchiChapter 99 Diagnosis and Natural History of Intraductal Papillary Mucinous Neoplasms (pages 918–923): L. William Traverso and Richard A. KozarekChapter 100 Mucinous Cystic Neoplasm (pages 924–931): Suresh T. Chari and Thomas C. SmyrkChapter 101 Surgical Treatment and Long?Term Outcome of Cystic Neoplasms of the Pancreas (pages 932–939): Carlos Fernandez?Del Castillo and Andrew L. WarshawChapter 102 Minimally Invasive and Local Ablation Techniques of Serous and Mucinous Cystic Lesions (pages 940–946): Laureano Fernandez?CruzChapter 103 Transplantation of Pancreatic Islets (pages 947–959): Reinhard G. Bretzel and Mathias D. BrendelChapter 104 Transplantation of the Pancreas (pages 960–969): Markus K. Muller and Hans W. Sollinger