ENGLISH

Drug - Drug Interactions (Drugs and the Pharmaceutical Sciences)

By A. David Rodrigues

Book information

Year
2001
ISBN
0824702832, 9780824702830, 9780585407067
LCC
RM302 .D784 2002
Open Library ID
OL3585359M
Language
english
Format
PDF
Filesize
4 MB (4572164 bytes)
Edition
1st
Pages
650\669
Time added
2011-06-04 13:46:07

Description

This reference presents comprehensive coverage of the preclinical, clinical, toxicological, regulatory, and marketing perspectives of metabolism-based drug-drug interactions-relating pharmacokinetic concepts to Michaelis-Menten kinetics. The book provides helpful examples, representative enzyme systems, and computer-aided modeling to clarify key concepts. It offers nearly 200 useful tables, equations, drawings, and photographs, and contributions by world-renowned experts in the field. They discuss kinetics-based in vitro-in vivo correlations, methods for the development of a metabolic drug interaction (MDI) database, and more.

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